Aim: This study aimed to assess the factors influencing decision making about living donation among medical students.
Method: Three standardized survey questionnaires (the Altruism Questionnaire A-N, the Individual Questionnaire for studying approaches to transplantology, the Interpersonal Reactivity Index) were used among 316 students of nursing and paramedics.
Results: Nearly all the respondents (98%) approve cell transplantation, tissue transplantation, and organ transplantation if obtained from living donors. Of the respondents, 66% would consent to donate bone marrow, and 26% would give their consent only in specific situations. Most respondents reported to be encouraged to donate organs by the ability to help other people (56%), while their refusal would be because of the fear of undergoing medical procedures (13%). Older age and a higher score in the personal distress subscale are correlated with a lack of consent to donate bone marrow for transplantation. In the case of living organ donation, the increase in the scores in the fantasy scale caused a higher chance for consent to living donation, whereas older age was the predictor of lack of consent. Higher scores in the perspective taking subscale were found to be significantly correlated with fear of surgical treatment as the reason for refusing to give one's consent to living donation. The belief that willingness to become a donor shows a person who has a sense of prosocial behavior was influenced by the fantasy and the empathic concern subscales.
Conclusions: The study group approves cell transplantation, tissue transplantation, and organ transplantation from living donors. These attitudes are determined by empathic behavior.
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http://dx.doi.org/10.1016/j.transproceed.2020.03.049 | DOI Listing |
Annu Rev Med
January 2025
SSM Health Saint Louis University Hospital Transplant Center, Saint Louis University, St. Louis, Missouri, USA; email:
Living-donor kidney transplantation is the preferred treatment for kidney failure. In the United States, rates of living kidney donation have been stagnant, which is partly related to concerns over medical and financial risks. Recent research has better characterized the risks of living kidney donation, although the field is limited by a lack of robust registries.
View Article and Find Full Text PDFClin Transplant
February 2025
MEDIC, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.
Optimizing the long-term care and follow-up of living kidney donors (LKDs) has been challenging, and prior LKDs have reported suboptimal healthcare experiences. Long-term care of LKDs is largely undertaken by primary care practitioners such as family physicians (FPs). We conducted a cross-sectional survey of Canadian FPs (n = 151).
View Article and Find Full Text PDFActa Obstet Gynecol Scand
January 2025
Department of Gynecology, Rennes University Hospital, Hôpital Sud, Rennes, France.
Introduction: Graft optimization is a necessity in order to develop uterus transplantation from brain-dead donors, as a complement to living donors, as these grafts are rare and the last organs retrieved in multiple organ donation. The aim of this study was to assess the feasibility and interest of hypothermic machine perfusion (HMP) in uterus transplantation using a porcine model; secondary outcomes were the evaluation of the graft's tolerance to a prolonged cold ischaemia time and to find new biomarkers of uterus viability.
Material And Methods: Fifteen uterus allotransplantations were performed in a porcine model, after 18 h of cold ischaemia, divided in three groups: Static cold storage in a HTK solution, HMP (with the VitaSmart (™) machine Bridge to Life Ltd.
Microbiome
January 2025
Division of Gastroenterology, Hepatology, and Nutrition, The Children's Hospital of Philadelphia, Philadelphia, PA, 19146, USA.
Background: The evolving infant gut microbiome influences host immune development and later health outcomes. Early antibiotic exposure could impact microbiome development and contribute to poor outcomes. Here, we use a prospective longitudinal birth cohort of n = 323 healthy term African American children to determine the association between antibiotic exposure and the gut microbiome through shotgun metagenomics sequencing as well as bile acid profiles through liquid chromatography-mass spectrometry.
View Article and Find Full Text PDFLancet Child Adolesc Health
February 2025
Stellenbosch University, Faculty of Medicine and Health Sciences, Department of Paediatrics and Child Health, Desmond Tutu TB Centre, Tygerberg, South Africa.
Background: There are few data on the treatment of children and adolescents with multidrug-resistant (MDR) or rifampicin-resistant (RR) tuberculosis, especially with more recently available drugs and regimens. We aimed to describe the clinical and treatment characteristics and their associations with treatment outcomes in this susceptible population.
Methods: We conducted a systematic review and individual participant data meta-analysis.
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