Introduction: In this retrospective study, the aim is to determine the sensitivity of maximum intensity projection (MIP) technique to 3 mm-thick axial sections in patients with small pulmonary nodules identified via examination using computed tomography (CT), and to identify whether this technique provides significant reduction in duration of nodule evaluation.
Materials And Methods: A total of 69 patients (339 nodules) who underwent thoracic tomography due to various complaints and in whom pulmonary nodules were identified as a result of the examination were included in the study. Their axial sections that are 3 mm-thick and MIP sections obtained in the axial plane were evaluated by two different radiologists at different times by keeping time. The dimensions and evaluation times of the nodules were recorded separately for each method.
Result: Evaluation compatibility between the radiologists was found to be 86.8% and it was considered to be perfectly compatible. Sensitivity of the 1st radiologist in the detection of nodules with MIP was 81.4%, whereas the sensitivity of the 2nd radiologist was 83.4%. In the evaluation for the reporting periods, when the duration of evaluation of MIP images were compared with the gold standard, a statistically significant reduction was found in the reporting times of both radiologists (p< 0.01).
Conclusions: It was found that utilization of MIP images as an alternative method to detect pulmonary modules reduces the duration of evaluation significantly and provides the ability to detect nodules with high sensitivity. According to these data, MIP imaging may be preferred as an adjunct method in the evaluation of lung nodules as it provides fast and reliable information besides classical axial sections.
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http://dx.doi.org/10.5578/tt.68561 | DOI Listing |
Int J Surg
January 2025
Department of Thoracic Surgery, Shanghai General Hospital Shanghai Jiao Tong University School of Medicine, Shanghai, PRC.
Background: The localization of pulmonary nodules is crucial for surgical intervention. However, a safe, simple, and efficient method remains elusive. This study aims to evaluate the safety and feasibility of a newly developed preoperative localization method for pulmonary nodules called Rapid Localization of Pulmonary Nodules On-Site (RLPN-OS).
View Article and Find Full Text PDFJTO Clin Res Rep
February 2025
Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, New York.
Introduction: Limited information exists on next-generation sequencing (NGS) success for lung tumors of 30 mm or less. We aimed to compare NGS success rates across biopsy techniques for these tumors, assess DNA sequencing quality, and verify reliability against surgical resection results.
Methods: We used data from the Initiative for Early Lung Cancer Research on Treatment study, including patients with lung tumors measuring 30 mm or less who had surgery and NGS on biopsies since 2016.
Background: Radiomics provides quantitative features of pulmonary nodules (PNs) which could aid lung cancer diagnosis, but medical image acquisition variability is an obstacle to clinical application. Acquisition effects may differ between radiomic features from benign vs. malignant PNs.
View Article and Find Full Text PDFJ Comput Assist Tomogr
January 2025
Centre for Biomedical Engineering, Indian Institute of Technology Delhi.
Objective: Early diagnosis of primary and metastatic lung nodules is critical for effective therapeutic planning. Manual delineation of lung nodules is not time-efficient and is prone to human error as well as interobserver and intraobserver variability. This study aimed to address the unmet need for an open-source computer-aided detection (CAD) system for 3D segmentation of lung and metastatic lung nodules along with radiomic feature extraction.
View Article and Find Full Text PDFACR Open Rheumatol
January 2025
Olgahospital, Klinikum Stuttgart, Germany.
Objective: Pulmonary involvement in chronic nonbacterial osteomyelitis (CNO) is rare. Limited awareness results in diagnostic challenges, especially because malignancy or infection needs to be considered.
Methods: Based on a survey shared among centers participating in the Kerndokumentation Deutsches Rheumaforschungszentrum (Germany), this study investigated clinical and imaging presentations, demographic features, treatment response and outcomes of pulmonary involvement in CNO (pCNO).
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