Summary: Rtpca is an R package implementing methods for inferring protein-protein interactions (PPIs) based on thermal proteome profiling experiments of a single condition or in a differential setting via an approach called thermal proximity coaggregation. It offers user-friendly tools to explore datasets for their PPI predictive performance and easily integrates with available R packages.
Availability And Implementation: Rtpca is available from Bioconductor (https://bioconductor.org/packages/Rtpca).
Supplementary Information: Supplementary data are available at Bioinformatics online.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058776 | PMC |
| http://dx.doi.org/10.1093/bioinformatics/btaa682 | DOI Listing |
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