Introduction: Loss of reduction after operative fixation of volarly unstable distal radius fractures with a volar lunate facet fragment (VLF) is considered problematic because it results in carpal subluxation or dislocation and subsequent impaired function. We hypothesized that the indicator of loss of reduction of the VLF after fixation is plate coverage of the bony fragment. We investigated the relationship between the plate coverage of the VLF and loss of reduction after fixation, and calculated the plate coverage that was associated with failure of fixation of the VLF.
Materials And Methods: We conducted a retrospective review. We included patients with surgically treated volarly unstable distal radius fractures with VLF with a volar locking plate who had a minimum follow-up of 6 months. A total of 33 patients (35 wrists) met criteria for inclusion into the study. The patients were divided into a displacement group and a non-displacement group. We calculated and compared longitudinal dimension and plate coverage of the VLF between the two groups to reveal the risk factors for loss of reduction.
Results: At final follow-up, 25 fractures maintained radiographic alignment and 10 (28.6%) lost reduction. Univariate analysis between the two groups showed that plate coverage against the transverse and longitudinal dimension of the VLF was correlated with loss of reduction after operative fixation. In multivariate logistic regression analysis, only plate coverage against the longitudinal dimension of the VLF remained a significant predictor of failure. With 64.7% as the cut-off point for plate coverage against the longitudinal dimension of the VLF, the sensitivity and specificity of the prediction were 96% and 80%, respectively.
Conclusion: The predictor of loss of reduction after fixation of volarly unstable distal radius fractures with a VLF was plate coverage against the longitudinal dimension of the VLF.
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http://dx.doi.org/10.1051/sicotj/2020026 | DOI Listing |
J Proteome Res
January 2025
Discovery Research, AbbVie, Inc., 1 North Waukegan Rd., North Chicago, Illinois 60064, United States.
Affinity capture (AC) combined with mass spectrometry (MS)-based proteomics is highly utilized throughout the drug discovery pipeline to determine small-molecule target selectivity and engagement. However, the tedious sample preparation steps and time-consuming MS acquisition process have limited its use in a high-throughput format. Here, we report an automated workflow employing biotinylated probes and streptavidin magnetic beads for small-molecule target enrichment in the 96-well plate format, ending with direct sampling from EvoSep Solid Phase Extraction tips for liquid chromatography (LC)-tandem mass spectrometry (MS/MS) analysis.
View Article and Find Full Text PDFAnn Work Expo Health
January 2025
Institute for Risk Assessment Sciences, Utrecht University, Yalelaan 2, 3584 CM Utrecht, the Netherlands.
Objectives: Trichloroethylene (TCE) is a carcinogen that has been causally linked to kidney cancer and possibly other cancer sites including the liver and lymphatic system. Its use in China has increased since the early 1990s due to the growing metal and electronic industries. We aimed to summarize the major sources of occupational exposure to TCE over time in China.
View Article and Find Full Text PDFWorld J Urol
January 2025
Urology Department, Urology and Nephrology Center, Mansoura University, Mansoura, Egypt.
Purpose: To compare between the dartos and tunica vaginalis flaps as covering layers in denovo distal or mid-shaft penile hypospadias underwent tubularized incised plate (TIP) repair.
Methods: This is a single-center, randomized trial was for denovo distal or mid-shaft penile hypospadias. Children with history of orchiectomy, orchiopexy and inguinal hernia repair were excluded.
Langmuir
January 2025
Research Focus Area for Chemical Resource Beneficiation, Catalysis and Synthesis Research Group, North-West University, 11 Hoffman Street, Potchefstroom 2522, South Africa.
This study investigates the surfactant properties and efficiency of linear and Guerbet-type amino acid surfactants. Utilizing a Wilhelmy plate method, we assessed the colloidal efficiency of these surfactants, with the lowest observed critical micelle concentration at 0.046 mmol L, significantly reducing surface tension to as low as 25.
View Article and Find Full Text PDFJ Orthop Case Rep
January 2025
Department of Orthopedics, Sree Balaji Medical College and Hospital, BIHER, Chromepet, Chennai, Tamil Nadu, India.
Introduction: Distal femur fractures present significant surgical challenges due to their complex anatomy and limited soft tissue coverage. Minimally invasive plate osteosynthesis (MIPO) has emerged as a promising alternative to traditional open techniques, aiming to reduce soft-tissue damage while maintaining stable fixation, particularly when used with locking plates.
Materials And Methods: This retrospective study analyzed 40 consecutive patients with distal femur fractures treated with MIPO and locking plates.
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