Severity: Warning
Message: file_get_contents(https://...@pubfacts.com&api_key=b8daa3ad693db53b1410957c26c9a51b4908&a=1): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
Filename: helpers/my_audit_helper.php
Line Number: 176
Backtrace:
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 176
Function: file_get_contents
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 250
Function: simplexml_load_file_from_url
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 1034
Function: getPubMedXML
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3152
Function: GetPubMedArticleOutput_2016
File: /var/www/html/application/controllers/Detail.php
Line: 575
Function: pubMedSearch_Global
File: /var/www/html/application/controllers/Detail.php
Line: 489
Function: pubMedGetRelatedKeyword
File: /var/www/html/index.php
Line: 316
Function: require_once
Introduction Weaning patients of ventilation is an important step in the intensive care unit; therefore, assessing the perfect timing to do such critical action is of equal significance to prevent complications. Rapid shallow breathing index (RSBI) has been used as a prediction tool for weaning adult patients, but for pediatric patients it is still an area of unclarity. Accordingly, the aim of this study is to evaluate the RSBI as a predictor of extubation outcome in pediatric patients underwent cardiac surgery at King Faisal Cardiac Center from 2016 until 2019. Methods A retrospective cohort study was conducted at King Faisal Cardiac Center on all extubated children having cardiac surgeries from 2016 to 2019 with excluding the patients who were admitted for causes other than cardiac surgery. Their age was ranged from birth until 14 years. Moreover, the patients were grouped based on the extubation outcomes into: success, success with non-invasive ventilation, or failure which was defined as reintubation within 48 hours after extubation. Regarding the collected data, three readings of RSBI on hourly basis prior to extubation were calculated by dividing respiratory rate (RR) over tidal volume (VT) with a correction based on the body weight. Results A total of 86 patients met the inclusion and exclusion criteria. Thirty (34.9%) patients were successfully extubated, 51 (59.3%) patients had successful extubation with the use of non-invasive ventilation, and only five (5.8%) patients suffered from extubation failure. Two-hour RSBI as a predictor of outcome had a P-value of 0.003, one-hour RSBI had a P-value of 0.01, RSBI at time of extubation had a P-value of 0.02. Mean corpuscular volume (MCV) is higher in extubation failure group with a p-value of 0.01. Conclusion This study suggests that pediatric patients who suffer from extubation failure usually have a higher RSBI measurement compared to the patients who have a successful extubation. The most significant RSBI measurements to predict the extubation outcome were recorded two hours prior to extubation. Our study also found that extubation failure patients could have higher MCV than the success group.
Download full-text PDF |
Source |
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7377672 | PMC |
http://dx.doi.org/10.7759/cureus.8754 | DOI Listing |
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