The presence of gastroesophageal reflux disease increases the risk of developing postoperative shoulder stiffness after arthroscopic rotator cuff repair.

Background: Postoperative shoulder stiffness (SS) after arthroscopic rotator cuff (RC) repair has been reported with a variable incidence, and numerous preoperative risk factors have been described. This prospective study aimed to document the incidence of postoperative SS and to evaluate the role of preoperative risk factors in the development of this complication, with a special focus on the role of gastroesophageal reflux disease (GERD).

Methods: Preoperative risk factors for SS were prospectively evaluated in 237 consecutive patients undergoing arthroscopic single-row RC repair. The presence of GERD was evaluated with the GerdQ diagnostic tool. Postoperative SS was diagnosed according to the criteria described by Brislin et al in 2007.

Results: The incidence of postoperative SS was 8.02%. The presence of GERD was significantly associated with the development of postoperative SS (odds ratio [OR], 5.265; 95% confidence interval [CI], 1.657-1.731; P = .005). Older age (OR, 0.896; 95% CI, 0.847-0.949; P < .001), male sex (OR, 0.126; 95% CI, 0.0252-0.632; P = .012), and number of pregnancies (OR, 0.47; 95% CI, 0.228-0.967; P = .040) emerged as protective factors.

Conclusions: The presence of GERD significantly influences the development of postoperative SS after arthroscopic single-row RC repair. An underlying aspecific proinflammatory condition, characterized by increased expression of tumor necrosis factor α and transforming growth factor β, and disorders in retinoid metabolism are hypotheses that could explain this previously unknown association. The documented incidence of postoperative SS falls within previously reported ranges, with women being significantly more affected than men.