Chronic rhinosinusitis (CRS) is one of the most common chronic medical conditions worldwide, affecting all age groups [...].
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| http://dx.doi.org/10.3390/jcm9072285 | DOI Listing |
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Endotyping in Chronic Rhinosinusitis-An EAACI Task Force Report.
Allergy
January 2025
Center for Rhinology and Allergology, Wiesbaden, Germany.
Chronic rhinosinusitis (CRS) is a clinical syndrome defined by typical sinonasal symptoms persisting for at least 12 weeks. CRS is divided into two distinct phenotypes, CRS with nasal polyps (CRSwNP) and without (CRSsNP). The aim of the review is to provide an update on the current knowledge in CRS endotypes.
View Article and Find Full Text PDFThe Role of Mesenchymal Stem Cells in the Treatment of a Chronic Rhinosinusitis-An In Vivo Mouse Model.
Microorganisms
May 2021
II-nd Department of Otolaryngology, Iuliu Hațieganu University of Medicine and Pharmacy, 400015 Cluj-Napoca, Romania.
It is acknowledged that the treatment of chronic rhinosinusitis (CRS) represents an important challenge for rhinology and for social and economic life. At present, one of the most common treatments for CRS is represented by local corticosteroids followed by endoscopic sinus surgery (ESS). Starting from the example of the mesenchymal stem cell's (MSC) capacity to migrate and to modulate a real response in the nasal mucosa of an allergic rhinitis mouse model, we try to obtain a response in a CRS mouse model, using MSC derived by adipose tissue.
View Article and Find Full Text PDFChronic Rhinosinusitis-An Update on Epidemiology, Pathogenesis and Management.
J Clin Med
July 2020
Iuliu Hatieganu University of Medicine and Pharmacy Cluj-Napoca, 400015 Cluj-Napoca, Romania.
Chronic rhinosinusitis (CRS) is one of the most common chronic medical conditions worldwide, affecting all age groups [...
View Article and Find Full Text PDFThe validity of nasal endoscopy in patients with chronic rhinosinusitis-An inter-rater agreement study.
Clin Otolaryngol
February 2018
Department of Otorhinolaryngology, Odense University Hospital, Odense, Denmark.
Objectives: Nasal endoscopy is a cornerstone in diagnosing sinonasal disease, but different raters might generate different results using the technique. Our study aims to evaluate the agreement between multiple raters to assess the validity of nasal endoscopy.
Design/participants: Three independent and blinded raters evaluated 28 patients (56 nasal cavities) diagnosed with chronic rhinosinusitis according to the European Position Paper on Rhinosinusitis and Nasal Polyps.
Limited evidence: higher efficacy of nasal saline irrigation over nasal saline spray in chronic rhinosinusitis--an update and reanalysis of the evidence base.
Otolaryngol Head Neck Surg
January 2014
Department of Otorhinolaryngology and Head & Neck Surgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, the Netherlands.
Objective: To assess the effectiveness of nasal saline irrigation in adult patients with chronic rhinosinusitis.
Data Sources: PubMed, EMBASE, the Cochrane Library.
Review Methods: A comprehensive search was performed, and 2 authors independently screened publications.
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