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Biomedicines
October 2024
Department of Innovative Technology in Medicine and Dentistry, Center of Advanced Studies and Technology, University of Chieti, 66100 Chieti, Italy.
The mouth and the oropharyngeal system are home to numerous bacterial species that constitute the so-called oral microbiome and play an important role for the integrity of the oral cavity, influencing the overall health of the body, as demonstrated by several studies. The aim of this study was to evaluate the bacterial modulation potential of a toothpaste (bioredoxin) containing curcumin and melatonin. Both substances have anti-inflammatory properties, as documented in several scientific reports.
View Article and Find Full Text PDFGeorgian Med News
September 2024
Department of Pediatric and Preventive Dentistry, University of Pristina, Faculty of Dentistry, Department of Diagnostic Sciences-Oral and Maxillofacial Radiology, Tufts University, School of Dental Medicine, United States.
This study aims to summarize the evidence of the effectiveness of xylitol toothpastes with a focus on caries, namely on its prevention and reduction. Materials and methods: A thorough literature review was performed after conducting an electronic search through Medline, PubMed (Central), Scopus, Web of Science (Scielo), Google scholar, and the Cochrane Library (from 2000 to November 2022) to identify studies relevant to the effectiveness of xylitol toothpastes in caries prevention. Results: The number of studies that have been found in the literature to meet the criteria for inclusion in this article has been limited.
View Article and Find Full Text PDFCompend Contin Educ Dent
November 2024
Senior Vice President and Distinguished Fellow, Clinical Research, Colgate-Palmolive Co., Piscataway, New Jersey.
Background: Oral malodor, whether from systemic disease, dietary sources, or bacteria in the oral cavity, can negatively impact patients' quality of life. Oral malodor due to bacteria in the oral cavity can be managed by mechanically or chemically removing bacteria. Dentifrices are ideal vehicles to deliver therapeutic active ingredients that promote and maintain oral health since most consumers brush their teeth daily.
View Article and Find Full Text PDFJ Dent
August 2024
Institute of Dentistry, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK. Electronic address:
Objectives: The objective of this systematic review was to assess the efficacy of topical applications containing surface pre-reacted glass-ionomer filler on dental hard tissues.
Data Sources: A comprehensive literature search was conducted in PubMed, MEDLINE, Embase, Scopus, ClinicalTrials.gov, Lilacs and Cochrane Central Register of Controlled Trials (until 15.
Heliyon
October 2023
Department of Drug and Food Control, Faculty of Pharmacy, Kerman University of Medical Sciences, Kerman, Iran.
The key characteristics of mesoporous hydroxyapatite, such as high porosity and expansive surface area, along with its biocompatibility with dental tissues and potential as a delivery vehicle for active ingredients, have recently garnered significant research focus. In the present study, mesoporous hydroxyapatite was synthesized using a precipitation technique and was subsequently characterized via X-ray diffraction, Fourier transform infrared, dynamic light scattering, field emission scanning electron microscopy and N adsorption-desorption isotherms. The results revealed that the synthesized mesopore particles exhibited significant adsorption potential, and were thereby considered a carrier of thymol, an effective antibacterial on oral pathogens.
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