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Frequency and types of antibiotic usage in a referral neonatal intensive care unit, based on the world health organization classification (AwaRe).
BMC Pediatr
January 2025
Student Research Committee, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Background: Excessive prescription of antibiotics in infants increases the risk of short-term and lifelong morbidity and mortality. Nonetheless, the use of antibiotics in neonatal intensive care units (NICUs) is significantly high. This is primarily because neonatologists are concerned about the fragile immune systems of newborns, their vulnerability to serious infectious diseases, and the challenge of accurately distinguishing between infectious and non-infectious conditions.
View Article and Find Full Text PDFChallenges in managing osteogenesis imperfecta in a resource-limited setting: a case report.
J Med Case Rep
January 2025
Lacor Hospital-Gulu, Gulu, Uganda.
Introduction: Osteogenesis imperfecta is a rare inherited connective tissue disorder that results in excessive bone fragility due to defects in collagen production. The majority of osteogenesis imperfecta cases are inherited in an autosomal dominant pattern, and 17 genetic causes have been identified. Diagnosis is usually based on clinical presentation and low bone mineral density scores, while treatment involves a multidisciplinary approach using medical therapies such as bisphosphonates, vitamin C, and pamidronate.
View Article and Find Full Text PDFPeripheral Intravenous Catheter-Associated Injuries in Neonates: Monitoring, Diagnosis, Management, and Complications.
Neoreviews
January 2025
Division of Neonatology, Department of Pediatrics, University of Maryland School of Medicine, Baltimore, Maryland.
Advances in neonatal medicine over the last several decades have led to improvements in survival for the most fragile and critically ill infants. A mainstay of supporting the health needs of hospitalized infants involves use of peripheral intravenous (PIV) catheters to administer medications, parenteral nutrition, and blood products. However, PIV catheters are not without risks and complications such as infiltration and extravasation.
View Article and Find Full Text PDFBarriers and facilitators for preventing mother-to-child transmission of Trypanosoma cruzi and hepatitis B in the Gran Chaco region: a qualitative analysis using the consolidated framework for implementation research (CFIR).
BMC Prim Care
December 2024
Fundación Mundo Sano, Buenos Aires, Argentina.
Background: Mother-to-child transmission (MTCT) of Trypanosoma cruzi and hepatitis B virus (HBV) increases morbidity and disability in Latin America and the Caribbean. The tailormade comprehensive antenatal care based on the Framework for the elimination of MTCT of HIV, syphilis, hepatitis B virus (HBV), and Chagas disease (EMTCT Plus) has been implemented in the region since 2018 through a private-public partnership. This study aimed to estimate the effectiveness of the intervention in preparing MTCT of T.
View Article and Find Full Text PDFTechnique and protocol for bedside neuroendoscopic lavage for post-hemorrhagic hydrocephalus: technical note.
Childs Nerv Syst
December 2024
Division of Neurosurgery, Department of Surgery, Children's Hospital of Philadelphia, Hub for Clinical Collaboration, 3500 Civic Center Boulevard, 10th floorfloor, Philadelphia, PA, 19104, USA.
Neuroendoscopic lavage (NEL) is a time-limited neurosurgical intervention that removes intraventricular blood in post-hemorrhagic hydrocephalus (PHH). Preterm neonates are medically complex and fragile, often precluding neurosurgical procedures due to concerns such as extubation risk and body temperature instability during even routine clinical care. In addition, transportation to the operating room can be difficult and risky.
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