The objectives of this research were to quantify and model daily feed intakes to 28 d of lactation in modern sows. A total of 4,512 daily feed intake (DFI) records were collected for 156 Hypor sows from February 2015 to March 2016. The mean lactation length was 27.9 ± 2.0 d. The data included 9 parity 1, 33 parity 2 and 114 parity 3+ sows. Data were collected using a computerized feeding system (Gestal Solo, JYGA Technologies, Quebec, Canada). The feeding system was used to set an upper limit to DFI for the first 7 d of lactation. Overall, the least-squares means of a model including the random effect of sow indicated that DFI's continued to slowly increase to 28 d of lactation. The DFI data were fitted to Generalized Michaelis-Menten (GMM) and polynomial functions of day of lactation (t). The GMM function [DFI (kg/d) = DFI + (DFI - DFI)(t/K)/[1 + (t/K)]] was fitted with 2 random effects for DFI (dfi) and intercept (dfi) using the NLMIXED procedure in SAS®. The polynomial function DFI (kg/d) = [B + B t + B t + B t + B t] was fitted with three random effects for B, B, and B using the MIXED procedure in SAS®. Fixed effects models of the two functions had similar Akaike's Information Criteria (AIC) values and mean predicted DFI's. The polynomial function with 3 random effects provided a better fit to the data based on R 30 (0.81 versus 0.79), AIC (14,709 versus 15,158) and RSD (1.204 versus 1.321) values than the GMM function with two random effects. The random effect for B in the polynomial function allowed for the fitting of the function to lactation records that had decreased DFI after 15 d of lactation. The random effects for the polynomial function were used to sort the lactation records into three groups based on the derivative of the function at 21 d of lactation. Lactation records of the three groups had similar DFI the first two weeks of lactation (P > 0.40). The three groups of sows had substantially different DFI's after 18 d of lactation (P < 0.028). The differences in both actual and predicted DFI's between the three groups increased with each day of lactation to day 28 (P < 0.001). Mixed model polynomial functions can be used to identify sows with different patterns of DFI after 15 d of lactation.
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http://dx.doi.org/10.2527/tas2017-0016 | DOI Listing |
Nutr Res
December 2024
Faculty of Medicine Health and Life Science, Swansea University, Swansea, Wales, UK. Electronic address:
Limited research has examined the effect of meal composition on sleep. Based on previous research, we hypothesized that a low glycemic index (LGI) drink containing 50 g isomaltulose (Palatinose, GI = 32) would result in more N3 sleep, less rapid eye movement (REM) sleep, and better memory consolidation than a high glycemic index (HGI) drink containing 50 g glucose (GI = 100). Healthy males (n = 20) attended the laboratory on three occasions at least a week apart (one acclimatization night and two test nights).
View Article and Find Full Text PDFJ Pediatr Nurs
January 2025
Faculty of Nursing, Yarmouk University, Irbid, Jordan. Electronic address:
Background: Type 1 diabetes is the most common endocrine health condition among youth. Healthcare professionals must consider evidence-based guidelines in managing children and adolescents with diabetic ketoacidosis (DKA). The current study aims to assess the outcomes of implementing clinical guidelines by the American Diabetes Association to manage DKA among pediatrics in an emergency department in Palestine.
View Article and Find Full Text PDFMedicine (Baltimore)
January 2025
Department of Thoracic Surgery, Renmin Hospital of Wuhan University, Wuhan, China.
While recent studies suggested a potential causal link between type 1 diabetes mellitus (T1DM) but not type 2 diabetes mellitus (T2DM) and idiopathic pulmonary fibrosis (IPF), the involved mechanism remains unclear. Here, using a Mendelian randomization (MR) approach, we verified the causal relationship between the two types of diabetes mellitus and IPF and investigated the possible role of inflammation in the association between diabetes mellitus and IPF. Based on genome-wide association study (GWAS) summary data of T1DM, T2DM, and IPF, the univariable MR, multivariable MR (MVMR), and mediation MR were successively used to analyze the causal relationship.
View Article and Find Full Text PDFMedicine (Baltimore)
January 2025
Renmin Hospital of Wuhan University, Wuhan, Hubei Province, People's Republic of China.
Colorectal cancer (CRC) is one of the most common cancers worldwide and inflammation is believed to play an important role in CRC. In this study, we comprehensively analyzed the causal association between 91 circulating inflammatory cytokines and the risk of CRC using Mendelian randomization (MR). Based on genome-wide association study summary statistics, we examined the causal effects of 91 circulating inflammatory cytokines on CRC.
View Article and Find Full Text PDFMedicine (Baltimore)
January 2025
National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China.
The correlation between cathepsins and pulmonary arterial hypertension (PAH) is well-established, but the causative link between them remains uncertain. This study aimed to explore the causal role of circulating metabolites mediating cathepsins in PAH using Mendelian randomization (MR). A 2-sample 2-step MR method was used to identify causal relationship between cathepsins and PAH; causal relationship between circulating metabolites and PAH; and mediated effects of these circulating metabolites.
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