AI Article Synopsis

  • There was a 3.6% rate of bacterial or fungal coinfections in COVID-19 patients admitted during March to April 2020, with 152 cases observed.
  • The mortality rate for these coinfected patients was high at 57%, with 74% requiring intubation and over half (51%) of those with blood infections having central venous catheters.
  • Most patients (79%) had received antibiotics before their infections were confirmed, and there were specific cases of E. cloacae with metallo-β-lactamase production in 5 patients.

Article Abstract

We observed bacterial or fungal coinfections in COVID-19 patients admitted between March 1 and April 18, 2020 (152 of 4,267, 3.6%). Among these patients, mortality was 57%; 74% were intubated; 51% with bacteremia had central venous catheters. Time to culture positivity was 6-7 days, and 79% had received prior antibiotics. Metallo-β-lactamase-producing E. cloacae coinfections occurred in 5 patients.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417979PMC
http://dx.doi.org/10.1017/ice.2020.368DOI Listing

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