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Background: For complete disruption of the posterolateral corner (PLC) structures, operative treatment is most commonly advocated, as nonoperative treatment has higher rates of persistent lateral laxity and posttraumatic arthritis. Some studies have shown that acute direct repair results in revision rates upwards of 37% to 40% compared with 6% to 9% for initial reconstruction. In a recent study assessing the outcomes of acute repair of PLC avulsion injuries with 2 to 7 years of follow-up, patients with adequate tissue were shown to have a much lower failure rate than previously documented.

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Cell-based and extracellular vesicle-based MSC therapies for acute radiation syndrome affecting organ systems.

J Radiat Res

December 2024

Department of Hematology and Oncology, Research Institute for Radiation Biology and Medicine, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8553, Japan.

Exposure to ionizing radiation can induce harmful biological effects on the human body, particularly in cases of high-dose γ-irradiation affecting the gastrointestinal tract, bone marrow, skin and lung. Such exposures lead to lethal outcomes as individuals experience a breakdown in their immune system's ability to defend against pathogens, predisposing them to sepsis-induced multiple organ failures. Mesenchymal stromal/stem cells (MSCs) possess diverse biological characteristics, including immunomodulation, anti-inflammation and tissue regeneration.

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Article Synopsis
  • Childhood exposure to mild traumatic brain injury (mTBI) has been linked to increased involvement in criminal justice as adolescents and adults, but previous studies haven't established whether this connection is causal or just a coincidence.
  • This study aimed to determine if childhood mTBI directly causes later criminal justice involvement, using a large population-based cohort from Denmark, tracking health and legal data from 1995 to 2000.
  • Results showed that out of 343,027 participants, there was a positive association between a history of mTBI and increased criminal charges, suggesting a potential causal link warranting further investigation.
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Background: Wound healing typically occurs in 4 sequential stages: hemostasis, inflammation, proliferation, and remodeling. During the proliferation stage, the wound undergoes granulation, angiogenesis, and epithelialization. Granulation involves the growth of connective tissue and blood vessels to fill the wound space.

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Blast injuries: The experience of a level 1 trauma center.

Injury

January 2025

Emergency Department, Tel Aviv Sourasky Medical Center, Affiliated to the Faculty of Medical & Health Sciences, Tel Aviv University, Tel Aviv, Israel. Electronic address:

Background: There is a global surge in blast injuries, which are associated with high morbidity and mortality. To our knowledge, there are no guidelines for the management of blast injuries in the trauma bay.

Methods: This single-center retrospective cohort study utilized data on all patients admitted to our emergency department (ED) with terror- or combat-related injuries between October 7, 2023 (Gaza Iron Swords War onset) and February 4, 2024.

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