AI Article Synopsis
- The relationship between type 2 diabetes and cancer is debated, with some researchers suggesting it stems from shared risk factors like obesity and insulin resistance.
- There are also theories that diabetes might independently increase cancer risk through various molecular pathways.
- The review summarizes recent studies on how type 2 diabetes and antidiabetic medications affect cancer risk and prognosis.
Article Abstract
Debate is ongoing regarding the relationship between type 2 diabetes and cancer, and the pathways linking the two are incompletely understood. Some posit that the relationship hinges on a common predisposing factor such as obesity, insulin resistance, or chronic inflammation that increases the risk of cancer independently. Others speculate that diabetes acts as an independent risk factor for cancer because of other molecular pathways and interactions. Additionally, antidiabetic medications have been associated with changes in cancer risk. This review presents a summary of the latest studies and data concerning the relationships among type 2 diabetes, antidiabetic medications, cancer risk, and cancer prognosis.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7364450 | PMC |
| http://dx.doi.org/10.2337/cd19-0077 | DOI Listing |
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