AI Article Synopsis
- - The study investigates how traditional methods of exposing organisms to toxins, like metal contamination, can negatively impact the nutritional quality of algae and culture media, highlighting the need for better delivery methods.
- - Researchers explored the use of liposome encapsulation to mitigate dietary metal toxicity by preparing silver (Ag)-laden liposomes and assessing their impact on algae growth and toxicity.
- - Findings reveal that Ag-laden liposomes are less toxic than direct exposure to silver, leading to lower mortality rates, increased reproduction, and enhanced growth metrics, indicating a safer alternative for studying dietary metal effects.
Article Abstract
The toxic effects of various substances on () observed through traditional waterborne uptake may involve alterations to the nutritional quality of the contaminated algae and culture media. It is essential to find an alternative delivery method that will not affect the nutritional quality of 's diet in order to elucidate the mechanisms of dietary metal toxicity. Therefore, this study examined the application of liposome encapsulation on the dietary toxicity of . Ag-laden liposomes were prepared and the Ag encapsulation efficiency and inhibition effect on algae growth were examined. Then, acute and 14-day subchronic studies were performed to examine the effect of Ag-laden liposomes on . The EC for the 24 h immobilization test was 10.59 µg/L for Ag-laden liposomes and 3.07 µg/L for Ag. In terms of subchronic effects, the estimated ECx values under the Ag-laden liposome condition were always higher than the direct exposure condition. Furthermore, the bioaccumulation of Ag-laden liposomes was about 1.68 times lower than direct exposure. Generally, Ag-laden liposomes produced less efficient toxicity than direct exposure, e.g., lower mortality, production of more neonates, higher intrinsic rate of natural increase (r), earlier time to first brood, and higher enzyme activities.
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| http://dx.doi.org/10.1080/10934529.2020.1794444 | DOI Listing |
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Acute and subchronic toxicity of Ag-laden liposomes on : the effect of encapsulation.
J Environ Sci Health A Tox Hazard Subst Environ Eng
October 2020
School of Environment and Geo-informatics, China University of Mining and Technology, Xuzhou, China.
Article Synopsis
- - The study investigates how traditional methods of exposing organisms to toxins, like metal contamination, can negatively impact the nutritional quality of algae and culture media, highlighting the need for better delivery methods.
- - Researchers explored the use of liposome encapsulation to mitigate dietary metal toxicity by preparing silver (Ag)-laden liposomes and assessing their impact on algae growth and toxicity.
- - Findings reveal that Ag-laden liposomes are less toxic than direct exposure to silver, leading to lower mortality rates, increased reproduction, and enhanced growth metrics, indicating a safer alternative for studying dietary metal effects.
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