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| http://dx.doi.org/10.1210/endocr/bqaa103 | DOI Listing |
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Neuroprotective effect of long-term resistance physical exercise against memory damage elicited by a lipopolysaccharide-induced neuroinflammation model in male rats.
J Neurosci Res
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Graduate Program in Biomedical Sciences, Medical School, Federal University of the South Border, Chapecó, Brazil.
Resistance exercise training (RET) is considered an excellent tool for preventing diseases with an inflammatory background. Its neuroprotective, antioxidant, and anti-inflammatory properties are responsible for positively modulating cholinergic and oxidative systems, promoting neurogenesis, and improving memory. However, the mechanisms behind these actions are largely unknown.
View Article and Find Full Text PDFDifferent pharmacokinetics of lithium orotate inform why it is more potent, effective, and less toxic than lithium carbonate in a mouse model of mania.
J Psychiatr Res
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Department of Pharmacology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, S7N 5E5, Canada. Electronic address:
Lithium carbonate (LiCO) is a mainstay therapeutic for the prevention of mood-episode recurrences in bipolar disorder (BD). Unfortunately, its narrow therapeutic index is associated with complications that may lead to treatment non-compliance. Intriguingly, lithium orotate (LiOr) is suggested to possess unique uptake characteristics that would allow for reduced dosing and mitigation of toxicity concerns.
View Article and Find Full Text PDFHormonal and pheromonal studies on amphibians with special reference to metamorphosis and reproductive behavior.
Dev Growth Differ
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Department of Biological Science, Faculty of Science, Shizuoka University, Shizuoka, Japan.
In this article, we review studies which have been conducted to investigate the hormonal influence on metamorphosis in bullfrog (Rana catesbeiana) and Japanese toad (Bufo japonicus) larvae, in addition to studies conducted on the hormonal and pheromonal control of reproductive behavior in red-bellied newts (Cynops pyrrhogaster). Metamorphosis was studied with an emphasis on the roles of prolactin (PRL) and thyrotropin (TSH). The release of PRL was shown to be regulated by thyrotropin-releasing hormone (TRH) and that of TSH was evidenced to be regulated by corticotropin-releasing factor.
View Article and Find Full Text PDFIncreased prevalence of autoimmune thyroid disease after COVID-19: A single-center, prospective study.
Front Endocrinol (Lausanne)
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Endocrinology and Diabetes Unit, Papa Giovanni XXIII Hospital, Bergamo, Italy.
Article Synopsis
- The study investigated thyroid dysfunction and autoimmune thyroid disease (ATD) in 599 COVID-19 survivors three months after hospital admission, focusing on the prevalence of specific antibodies.
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Investigating thyroid dysfunction in the context of COVID-19 infection.
Ann Med Surg (Lond)
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Department of Biochemistry and Molecular Biology, Faculty of Life Science, Mawlana Bhashani Science and Technology University, Tangail, Bangladesh.
COVID-19 is a contagious viral infection caused by severe acute respiratory syndrome coronavirus 2 (Sars-CoV-2). One of the key features of COVID-19 infection is inflammation. There is increasing evidence pointing to an association between cytokine storm and autoimmunity.
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