Increasing naloxone awareness and carrying among individuals who misuse opioid analgesic medications (OAs) could reduce opioid overdose mortality. : Self-report surveys were completed by 322 adults receiving residential addiction treatment who misused OAs in the past year. Descriptive analyses and prevalence ratios (using Poisson generalized estimating equations) examined whether illegal opioid (e.g., heroin) initiation was associated with naloxone awareness. : Among this sample of participants who misused OAs, naloxone awareness was lowest among those who never used illegal opioids (26%) and highest among those who transitioned from OAs to illegal opioid use over time (83%). Naloxone awareness remained higher among participants who had used illegal opioids after adjustment for sociodemographic and substance use characteristics. Those who used OAs before initiating illegal opioids were 2.3-fold (95% CI: 1.5-3.3) more likely to have naloxone awareness than those who had only misused OAs after adjustment. Half of participants who had only used OAs had experienced an overdose, 75% had witnessed an overdose, and 61% were prescribed OAs to treat pain in the past 6 months. Implementing overdose education and naloxone distribution programs during addiction treatment could bolster naloxone awareness among people who misuse OAs but who have not used illegal opioids.
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http://dx.doi.org/10.1080/08897077.2020.1784361 | DOI Listing |
HCA Healthc J Med
December 2024
HCA Florida Orange Park Hospital, Orange Park, FL.
Introduction: As illicit drug manufacturers find new ways to market their products and increase their profit margins, multiple contaminants have found their way into the illicit drug supply. The newest addition, xylazine, also known as "tranq," has spread through the city of Philadelphia and has recently been gaining ground across the United States, including in the state of Florida.
Case Presentation: This case describes a 37-year-old male with a significant past psychiatric history of severe polysubstance intravenous (IV) use, including fentanyl and methamphetamine.
Harm Reduct J
December 2024
Buehler Center for Health Policy and Economics, Institute for Public Health and Medicine, Northwestern University, 420 E. Superior St. 9th Floor, Chicago, IL, 60611, USA.
Cureus
November 2024
Department of Anesthesia and Perioperative Medicine, London Health Sciences Centre, and St. Joseph Health Care, Lawson Health Research Institute, Schulich School of Medicine and Dentistry, Western University, London, CAN.
This case report describes a 62-year-old male who experienced paradoxical hypothermia following an elective total knee replacement (TKR) performed under spinal anesthesia with intrathecal morphine administration. The patient presented with significant hypothermia, defined as a body temperature below 35°C, approximately 45 minutes following the administration of anesthesia. The condition demonstrated resistance to conventional rewarming techniques.
View Article and Find Full Text PDFIndian J Psychol Med
June 2024
Indian Council of Medical Research-Centre for Ageing and Mental Health, Kolkata, West Bengal, India.
Int J Clin Pharm
February 2025
College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
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