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Background: The use of mechanical circulatory support devices for high-risk percutaneous coronary intervention (PCI) has increased over the past decade despite limited data of benefit. We sought to examine the association between intravascular microaxial left ventricular assist device (LVAD) versus intra-aortic balloon pump use in patients without cardiogenic shock (CS) undergoing PCI.
Methods And Results: This retrospective study analyzed claims data from a large, insured population who underwent PCI without CS from April 1, 2016 to July 31, 2022.
Use of Intravascular Micro-Axial Left Ventricular Assist Devices as a Bridging Strategy for Cardiogenic Shock: Mid-Term Outcomes.
J Clin Med
November 2024
Heart and Vascular Institute, Pennsylvania State Milton S Hershey Medical Center, Hershey, PA 17033, USA.
: Patients in cardiogenic shock (CS) may be successfully bridged using intravascular micro-axial left ventricular assist devices (M-LVADs) for recovery or determination of definitive therapy. : One hundred and seven CS patients implanted with M-LVADs from January 2020 to May 2024 were divided into four groups; group-1: 34 patients (transplant); group-2: 25 patients (LVAD); group-3: 42 patients (postcardiotomy CS (PCCS)); group-4: 6 patients (decision/recovery but excluded from analysis). Multivariable logistic regression and Multivariable Coxregression models identified predictors of early -hospital and late mortality, and Odds ratios (ORs) and hazard ratios (HRs) with < 0.
View Article and Find Full Text PDFImpact of Impeller Speed Adjustment Interval on Hemolysis Performance of an Intravascular Micro-Axial Blood Pump.
Micromachines (Basel)
July 2024
Department of Instrument Science and Engineering, Shanghai Jiao Tong University, Shanghai 200240, China.
Background: In recent years, intravascular micro-axial blood pumps have been increasingly used in the treatment of patients with cardiogenic shock. The flow rate of such blood pumps requires adjustment based on the patient's physiological condition. Compared to a stable flow state with fixed rotation speed, adjusting the speed of blood pump impeller to alter flow rate may lead to additional hemolysis.
View Article and Find Full Text PDFAutomated control of Impella maintains optimal left ventricular unloading during periods of unstable hemodynamics and prevents myocardial damage in acute myocardial infarction.
Int J Cardiol
September 2024
Department of Cardiovascular Dynamics, National Cerebral and Cardiovascular Center, Suita, Japan. Electronic address:
Article Synopsis
- The study focuses on an Automatic IMpella Optimal Unloading System (AIMOUS) designed to control the speed of the Impella pump, improving heart protection during cardiovascular diseases by maintaining left ventricular (LV) unloading effectively.
- Using an animal model, AIMOUS was validated to keep LV systolic pressure stable, showing success in managing fluctuations in blood volume without losing efficiency.
- Results indicated that AIMOUS significantly enhanced LV function and minimized heart tissue damage in acute ischemia-reperfusion situations compared to standard Impella support, suggesting its potential for better clinical outcomes.
Percutaneous intravascular micro-axial blood pump: current state and perspective from engineering view.
J Artif Organs
December 2024
Emeritus Professor of Hokkaido University, Sapporo, Japan.
The utilization of a minimally invasively placed catheter-mounted intravascular micro-axial flow blood pump (IMFBP) is increasing in the population with advanced heart failure. The current development of IMFBPs dates back around the 1990s, namely the Hemopump with a wire-drive system and the Valvopump with a direct-drive system. The wire-drive IMFBPs can use a brushless motor in an external console unit to transmit rotational force through the drive wire rotating the impeller inside the body.
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