Sparse signal representations have gained much interest recently in both signal processing and statistical communities. Compared to orthogonal matching pursuit (OMP) and basis pursuit, which solve the and constrained sparse least-squares problems, respectively, least angle regression (LARS) is a computationally efficient method to solve both problems for all critical values of the regularization parameter . However, all of these methods are not suitable for solving large multidimensional sparse least-squares problems, as they would require extensive computational power and memory. An earlier generalization of OMP, known as Kronecker-OMP, was developed to solve the problem for large multidimensional sparse least-squares problems. However, its memory usage and computation time increase quickly with the number of problem dimensions and iterations. In this letter, we develop a generalization of LARS, tensor least angle regression (T-LARS) that could efficiently solve either large or large constrained multidimensional, sparse, least-squares problems (underdetermined or overdetermined) for all critical values of the regularization parameter and with lower computational complexity and memory usage than Kronecker-OMP. To demonstrate the validity and performance of our T-LARS algorithm, we used it to successfully obtain different sparse representations of two relatively large 3D brain images, using fixed and learned separable overcomplete dictionaries, by solving both and constrained sparse least-squares problems. Our numerical experiments demonstrate that our T-LARS algorithm is significantly faster (46 to 70 times) than Kronecker-OMP in obtaining -sparse solutions for multilinear leastsquares problems. However, the -sparse solutions obtained using Kronecker-OMP always have a slightly lower residual error (1.55% to 2.25%) than ones obtained by T-LARS. Therefore, T-LARS could be an important tool for numerous multidimensional biomedical signal processing applications.
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Sensors (Basel)
January 2025
School of Artificial Intelligence, Beijing University of Posts and Telecommunications (BUPT), Beijing 100876, China.
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January 2025
Key Laboratory of Modern Acoustics, Institute of Acoustics, Nanjing University, Nanjing 210093, China.
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View Article and Find Full Text PDFSci Rep
January 2025
Fischell Department of Bioengineering, University of Maryland, College Park, USA.
The development of optical sensors for label-free quantification of cell parameters has numerous uses in the biomedical arena. However, using current optical probes requires the laborious collection of sufficiently large datasets that can be used to calibrate optical probe signals to true metabolite concentrations. Further, most practitioners find it difficult to confidently adapt black box chemometric models that are difficult to troubleshoot in high-stakes applications such as biopharmaceutical manufacturing.
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November 2024
Cancer Institute, Suzhou Medical College, Soochow University, NO. 199 Ren-ai Road, SIP, Suzhou 215000, China.
Alternative polyadenylation (APA) is an important driver of transcriptome diversity that generates messenger RNA isoforms with distinct 3' ends. The rapid development of single-cell and spatial transcriptomic technologies opened up new opportunities for exploring APA data to discover hidden cell subpopulations invisible in conventional gene expression analysis. However, conventional gene-level analysis tools are not fully applicable to APA data, and commonly used unsupervised dimensionality reduction methods often disregard experimentally derived annotations such as cell type identities.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Buildings and Construction Techniques Engineering, College of Engineering, Al-Mustaqbal University, Hillah, Babylon, 51001, Iraq.
The land use transition plays an important role for terrestrial environmental services, which had a mixed impact of positive and negative on the groundwater and terrestrial water resource. The health of ecological systems and groundwater depends on the mapping and management of land use. The Ganga basin is one of the most densely populated and agriculture-intensive river systems in the South Asia and the world.
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