The putative active metabolite of aeruginascin, a naturally occurring tryptamine of "magic mushrooms," has been synthesized and structurally characterized. Competitive radioligand binding assays demonstrate that it has a high affinity at human serotonin receptors 5-HT, 5-HT, and 5-HT, though it does not bind at the 5-HT receptor, where activity was previously predicted.
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| http://dx.doi.org/10.1021/acsomega.0c02208 | DOI Listing |
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