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Background: Chlorogenic acid is a type of phenolic acid found in many plants. Chlorogenic acid has an anti-obesity effect with an unclear mechanism. The present study aimed to investigate the regulatory effect of chlorogenic acid on energy balance in high-fat diet (HFD) induced obese C57BL/6J mice administrated 100 mg kg chlorogenic acid for 13 weeks.
Results: The consumption of chlorogenic acid ameliorated HFD induced obesity. Chlorogenic acid did not change the physical activity but significantly decreased food intake and increased body temperature, thermal dissipation and brown adipose tissue activity. Moreover, chlorogenic acid improved glucose tolerance but had a moderate impact on other blood indices. Additionally, chlorogenic acid failed to restore the microbiota change associated with HFD induced obesity, but modified the gut bacterial composition in a unique way.
Conclusion: Supplementation with chlorogenic acid can improve HFD induced obesity and associated glucose intolerance mainly via regulating food intake and energy expenditure. © 2020 Society of Chemical Industry.
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http://dx.doi.org/10.1002/jsfa.10675 | DOI Listing |
Wei Sheng Yan Jiu
November 2024
Shenzhen Center for Chronic Disease Control, Shenzhen 518020, China.
Objective: To detect phenolic acid compounds in various fruits and explore the differences in phenolic acids among different types of fruits.
Methods: The collected 75 types of fruits were classified into 6 categories: citrus、melon、drupe、berry、tropical fruit and pome fruits. The phenolic acid compounds were detected by high performance liquid chromatography-mass spectrometry.
Front Pharmacol
December 2024
School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Background And Aim: (Oliv.) Diels (Danggui, DG), exhibits potential in myocardial infarction (MI) treatment. However, research on its synergistic combinations for cardioprotective effects has been limited owing to inadequate approaches.
View Article and Find Full Text PDFFood Chem X
December 2024
College of Engineering in Jiangxi Agricultural University, Jiangxi Key Laboratory of Modern Agricultural Equipment Jiangxi Province, Nanchang 330045, China.
is widely used as healthy food and herbal medicine for its anti-inflammatory, analgesic, antihypertensive, and antiviral functions. The drying behavior and physicochemical quality of were studied to evaluate its adaptability under four drying techniques: hot air drying (HAD), medium-and short-wave infrared drying (MSWID), pulsed vacuum drying (PVD), and radio frequency-HAD (RF-HAD). Compared with HAD and MSWID, PVD and RF-HAD can form beneficial microporous channels for moisture migration inside , thus shortening drying time by 32.
View Article and Find Full Text PDFFront Plant Sci
December 2024
Department of Biochemistry, Faculty of Pharmacy, Harran University, Sanliurfa, Türkiye.
In this study, L. extracts were obtained using various green extraction techniques, including supercritical CO, subcritical ethanol, and ultrasound-assisted extraction, each performed under optimized parameters. The phytochemical content of the extracts was analyzed using the LC-MS/MS technique, quantifying 53 phytochemicals.
View Article and Find Full Text PDFInt J Biol Macromol
December 2024
School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou 510006, China; Department of Traditional Chinese Medicine, Institute of Guangdong Geriatric, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou 510080, China.
Thermosensitive hydrogels show great potential in healing diabetic wounds, but they are still challenged by the long healing time, risk of infectivity, and accumulation of melanin. Herein, a dual network hydrogel is designed, which consists of chlorogenic acid (CA) modified chitosan (CS) (CA@CS), poly(N-isopropylacrylamide) (PNIPAm), and glabridin liposomes (GL). The gelation transition temperature of the hydrogel is 32-34 °C, which thus endows it with superior injectability at ambient temperature.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!