An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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[Corrigendum] Overexpression of septin‑7 inhibits melatonin‑induced cell apoptosis in human fetal osteoblastic cells via suppression of endoplasmic reticulum stress.
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Department of Orthopaedics, First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110001, P.R. China.
Subsequently to the publication of this paper, an interested reader drew to the authors' attention that Figs. 2 and 4, featured on p. 4820 and 4821 respectively, contained apparently matching control β‑actin western blots.
View Article and Find Full Text PDFMelatonin induces Nrf2-HO-1 reprogramming and corrections in hepatic core clock oscillations in Non-alcoholic fatty liver disease.
FASEB J
September 2021
Division of Chronobiology and Metabolic Endocrinology, Department of Zoology, Faculty of Science, The Maharaja Sayajirao University of Baroda, Vadodara, India.
Melatonin pleiotropically regulates physiological events and has a putative regulatory role in the circadian clock desynchrony-mediated Non-alcoholic fatty liver disease (NAFLD). In this study, we investigated perturbations in the hepatic circadian clock gene, and Nrf2-HO-1 oscillations in conditions of high-fat high fructose (HFHF) diet and/or jet lag (JL)-mediated NAFLD. Melatonin treatment (100 µM) to HepG2 cells led to an improvement in oscillatory pattern of clock genes (Clock, Bmal1, and Per) in oleic acid (OA)-induced circadian desynchrony, while Cry, Nrf2, and HO-1 remain oblivious of melatonin treatment that was also validated by circwave analysis.
View Article and Find Full Text PDFCorrection: Melatonin-induced ApoE expression in mouse astrocytes protects endothelial cells from OGD-R induced injuries.
Transl Psychiatry
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An amendment to this paper has been published and can be accessed via a link at the top of the paper.
View Article and Find Full Text PDFDesynchronosis and erosive and ulcerative lesions of the stomach in rats active or passive in the open-field test: effect of exogenous melatonin.
Bull Exp Biol Med
March 2003
P. K. Anokhin Institute of Normal Physiology, Russian Academy of Medical Sciences, Moscow.
We studied the effect of a phase shift in circadian rhythms (desynchronosis) on the development of erosive and ulcerative lesions in the gastric mucosa in male Wistar rats with different behavioral activity in the open-field test. The animals kept under conditions of natural or shifted light-dark cycle were untreated or intraperitoneally received physiological saline (1 ml) and melatonin (1 or 2 mg/kg). Desynchronosis induced gastric ulcers in active rats not receiving injections or intraperitoneally injected with physiological saline.
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