In this paper, the application of a clipping and digital resolution enhancer (DRE) is numerically investigated in 56-GBaud direct-detection four-ary pulse amplitude modulation (PAM4) transmission systems. The influence of the tap length and the digital-to-analog converter (DAC) samples per symbol on DRE gain is first studied. After optimizing clipping probability, sampling jitter is introduced. The combination of clipping and DRE can increase jitter tolerance by ∼1.7% sampling time for 4-bit DAC. Then, the required optical signal-to-noise ratio (OSNR) at the hard-decision forward error correction (HD-FEC) threshold of 3.8×10 is investigated in back-to-back case and 80-km fiber transmission. It is shown that the combination of clipping and DRE can reduce the required OSNR significantly for 3-bit and 4-bit DAC. Finally, the performance gain introduced by clipping and DRE is analyzed from a perspective of the transmitted average signal power and the received mean-squared quantization error.
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http://dx.doi.org/10.1364/OE.394412 | DOI Listing |
J Appl Stat
April 2024
Department of Mathematical Sciences, University of Texas at El Paso, El Paso, TX, USA.
Early detection of prostate cancer is critical for successful treatment and survival. However, current diagnostic methods such as prostate-specific antigen (PSA) testing and digital rectal examination (DRE) have limitations in accuracy, specificity, and sensitivity. Recent research suggests that urinary volatile organic compounds (VOCs) could serve as potential biomarkers for prostate cancer diagnosis.
View Article and Find Full Text PDFBMJ Open
June 2023
Warwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, UK.
Introduction: Robotic-assisted knee replacement systems have been introduced to healthcare services worldwide in an effort to improve clinical outcomes for people, although high-quality evidence that they are clinically, or cost-effective remains sparse. Robotic-arm systems may improve surgical accuracy and could contribute to reduced pain, improved function and lower overall cost of total knee replacement (TKR) surgery. However, TKR with conventional instruments may be just as effective and may be quicker and cheaper.
View Article and Find Full Text PDFIn this paper, the application of a clipping and digital resolution enhancer (DRE) is numerically investigated in 56-GBaud direct-detection four-ary pulse amplitude modulation (PAM4) transmission systems. The influence of the tap length and the digital-to-analog converter (DAC) samples per symbol on DRE gain is first studied. After optimizing clipping probability, sampling jitter is introduced.
View Article and Find Full Text PDFChem Biol Interact
May 1996
Texas A&M University, College Station 77843-4466, USA.
Ligand-dependent differences in the molecular properties of the transformed cytosolic and nuclear aryl hydrocarbon receptor (AhR) were investigated using the proteolytic clipping band shift assay. AhR complexes were incubated with [32P]dioxin responsive element (DRE) (26-mer) or bromodeoxyuridine (BrdU)-DRE and the resulting protein-DNA or crosslinked protein-DNA complexes were treated with trypsin or V8 protease and analyzed by electrophoresis. The results showed that for several different AhR ligands including 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), 2,3,7,8-tetrachlorodibenzofuran, 1,2,7,8-tetrachlorodibenzofuran and alpha-naphthoflavone, the pattern of degraded protein-DNA products were similar using transformed cytosolic or nuclear AhR complexes.
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