High altitude reduces infection rate of COVID-19 but not case-fatality rate.

Respir Physiol Neurobiol

High Altitude Research Institute, Laboratories of Investigation and Development (LID), Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru.

Published: October 2020

Coronavirus disease 19 (COVID-19) is a pandemic caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). It is suggested that life at high altitude may reduce COVID-19 infections and case-fatality rates (cases/deaths). We study data from Peru COVID-19 pandemics, which first case was recorded on March 6th, 2020. By June 13, 2020 there were 6498 deaths, and 224,132 SARS-CoV-2 positives. Using data from 185 capitals of provinces with altitudes ranging from 3 to 4342 m, we confirm previous reports that infection with COVID-19 at high altitude is reduced. However, case-fatality rate is not dependent of altitude. We have also presented first evidence that female protection towards death by COVID-19 is reduced as altitude of residence increases.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7361094PMC
http://dx.doi.org/10.1016/j.resp.2020.103494DOI Listing

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