AI Article Synopsis

  • A systematic review highlights the importance of essential trace elements, especially Copper and Zinc, in neurodevelopment during key growth periods in children and adolescents (ages 3-16).
  • Deficiencies or imbalances in these microelements are linked to symptoms of inattention, hyperactivity, and impulsivity.
  • Previous research suggests that these trace elements correlate with cognitive functioning, indicating their potential role in various clinical issues faced by pediatric patients.

Article Abstract

Systematic review article reported that essential trace elements, mainly microelements Copper and Zinc (deficiency and high values concentration disbalance in blood) play significant roles in neurodevelopmental processes and are associated not only with inattention and hyperactivity, impulsivity symptoms among children and adolescents in the most critical active growth and development periods (between 3 and 16 years old). In the same time previous studies have proposed that clinical symptoms are significant associated their levels and positively correlated with cognitive symptomatology as trace bioactive substances. Their functional connectivity is different and is one of the serious problems for clinical pediatric.

Download full-text PDF

Source

Publication Analysis

Top Keywords

essential trace
8
trace elements
8
[modern insues
4
insues essential
4
elements level
4
level influence
4
influence children
4
children adulth
4
adulth health
4
health review]
4

Similar Publications

Apoptosis, or programmed cell death, is a fundamental biological process essential for maintaining tissue homeostasis. Dysregulation of apoptosis is implicated in a variety of diseases, including cancer, neurodegenerative disorders, and autoimmune conditions. This review provides an in-depth insight into the molecular mechanisms and signaling pathways that regulate apoptosis, highlighting both intrinsic and extrinsic pathways.

View Article and Find Full Text PDF

Spatial Transcriptomics: Biotechnologies, Computational Tools, and Neuroscience Applications.

Small Methods

January 2025

Department of Bioinformatics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, China.

Spatial transcriptomics (ST) represents a revolutionary approach in molecular biology, providing unprecedented insights into the spatial organization of gene expression within tissues. This review aims to elucidate advancements in ST technologies, their computational tools, and their pivotal applications in neuroscience. It is begun with a historical overview, tracing the evolution from early image-based techniques to contemporary sequence-based methods.

View Article and Find Full Text PDF

Bone defect repair remains a great challenge in the field of orthopedics. Human body essential trace element such as copper is essential for bone regeneration, but how to use it in bone defects and the underlying its mechanisms of promoting bone formation need to be further explored. In this study, by doping copper into mesoporous bioactive glass nanoparticles (Cu-MBGNs), we unveil a previously unidentified role of copper in facilitating osteoblast mitophagy and mitochondrial dynamics, which enhance amorphous calcium phosphate (ACP) release and subsequent biomineralization, ultimately accelerating the process of bone regeneration.

View Article and Find Full Text PDF

Effects of exogenous selenium application on quality characteristics, selenium speciation, and in vitro bioaccessibility of rice pancakes.

Food Chem X

January 2025

Cooperative Innovation Center of Industrial Fermentation (Ministry of Education & Hubei Province), Key Laboratory of Fermentation Engineering (Ministry of Education), National "111" Center for Cellular Regulation and Molecular Pharmaceutics, Hubei Key Laboratory of Industrial Microbiology, School of Life and Health Sciences, Hubei University of Technology, Wuhan, Hubei 430068, PR China.

Selenium is an essential trace element for human health. To date, a hotspot of functional foods is strengthening the content of organic Se in food using biological Se enrichment. Herein, Se-enriched rice pancakes were produced by directly adding different sodium selenite concentrations into the fermentation process.

View Article and Find Full Text PDF

SLC7A5 is required for cancer cell growth under arginine-limited conditions.

Cell Rep

January 2025

Department of Biochemistry, University of Utah, Salt Lake City, UT 84112, USA; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA. Electronic address:

Tumor cells must optimize metabolite acquisition between synthesis and uptake from a microenvironment characterized by hypoxia, lactate accumulation, and depletion of many amino acids, including arginine. We performed a metabolism-focused functional screen using CRISPR-Cas9 to identify pathways and factors that enable tumor growth in an arginine-depleted environment. Our screen identified the SLC-family transporter SLC7A5 as required for growth, and we hypothesized that this protein functions as a high-affinity citrulline transporter.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!