AI Article Synopsis
- * A comprehensive literature search yielded 22 original articles analyzing clinical outcomes and complications related to LITT, as well as insights from the authors' own experience.
- * Findings indicate that LITT is a safe and effective option for patients who haven't responded to Stereotactic Radiosurgery (SRS), but more research is needed on combining LITT with systemic therapies and optimizing treatment through new imaging techniques.
Article Abstract
Purpose: The aim of this paper is to discuss the current evidence for Laser Interstitial Thermal Therapy (LITT) in the treatment of brain metastases, our current recommendations for patient selection and the future perspectives for this therapy. We have also touched upon the possible complications and role of systemic therapy coupled with LITT for the treatment of brain metastases.
Material And Methods: Two authors carried out the literature search using two databases independently, including PubMed, and Web of Science. The review included prospective and retrospective studies using LITT to treat brain metastases.
Results: Twenty-two original articles were analyzed in this review, particularly clinical outcomes and complications. We have also provided our institutional experience in the use of LITT to treat brain metastases and addressed future perspectives for the use of this technology.
Conclusions: The current literature supports LITT as a safe and effective therapy for patients with brain metastases that have failed SRS. Larger studies are still required to better evaluate the use of systemic therapy in concomitance with LITT. New images modalities may enable optimized treatment and outcomes.
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| http://dx.doi.org/10.1080/02656736.2020.1748238 | DOI Listing |
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