AI Article Synopsis
- The study analyzed differences in the clinical profile and outcomes of COVID-19 patients admitted to a Spanish Emergency Department, categorizing them by age groups.
- It included 1,379 patients, finding that older individuals presented with fewer typical COVID symptoms and had worse short-term outcomes, such as higher mortality rates.
- The research suggests that age should be considered in treatment decisions for COVID-19 patients, as it significantly affects prognosis and management.
Article Abstract
Purpose: To determine the differences by age-dependent categories in the clinical profile, presentation, management, and short-term outcomes of patients with laboratory-confirmed COVID-19 admitted to a Spanish Emergency Department (ED).
Methods: Secondary analysis of COVID-19_URG-HCSC registry. We included all consecutive patients with laboratory-confirmed COVID-19 admitted to the ED of the University Hospital Clinico San Carlos (Madrid, Spain). The population was divided into six age groups. Demographic, baseline and acute clinical data, and in-hospital and 30-day outcomes were collected.
Results: 1379 confirmed COVID-19 cases (mean age 62 (SD 18) years old; 53.5% male) were included (18.1% < 45 years; 17.8% 45-54 years; 17.9% 55-64 years; 17.2% 65-74 years; 17.0% 75-84 years; and 11.9% ≥ 85 years). A statistically significant association was found between demographic, comorbidity, clinical, radiographic, analytical, and therapeutic variables and short-term results according to age-dependent categories. There were less COVID-specific symptoms and more atypical symptoms among older people. Age was a prognostic factor for hospital admission (aOR = 1.04; 95% CI 1.02-1.05) and in-hospital (aOR = 1.08; 95% CI 1.05-1.10) and 30-day mortality (aOR = 1.07; 95% CI 1.04-1.09), and was associated with not being admitted to intensive care (aOR = 0.95; 95% CI 0.93-0.98).
Conclusions: Older age is associated with less COVID-specific symptoms and more atypical symptoms, and poor short-term outcomes. Age has independent prognostic value and may help in shared decision-making in patients with confirmed COVID-19 infection.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363499 | PMC |
| http://dx.doi.org/10.1007/s41999-020-00359-2 | DOI Listing |
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