Purpose: To determine the vision-related quality of life (VR-QoL) and its dimensions in corneal transplant recipients.
Methods: This cross-sectional study was carried out on 100 patients who underwent penetrating keratoplasty. Data collection tools included a demographic questionnaire, satisfaction questionnaire, and Persian version of the 39-item National Eye Institute Visual Functioning Questionnaire (NEI-VFQ 39).
Results: The composite score of VR-QoL in corneal transplant recipients was 54.39 ± 9.22 (32.9-71.01). The highest mean score among subscales was related to color vision (74.75 ± 27.63) and the lowest related to dependency (31.06 ± 31.02). The results showed that there is a reverse correlation between VR-QoL with both age ( = -0.364; < 0.001) and the numbers of years after the transplantation ( = -0.362; < 0.001). However, there was a correlation between satisfaction and VR-QoL ( = 0.679; < 0.001). Furthermore, the results showed that there is a significant difference in VR-QoL between men and women ( < 0.001) and also a significant difference in VR-QoL between unilateral and bilateral graft recipients ( < 0.001).
Conclusions: The corneal transplant has the highest impact on color vision and the lowest on dependency. Moreover, the results of this study provide a comprehensive picture for the state of vision and overall health status of patients for health-care providers to enhance the patient care.
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http://dx.doi.org/10.4103/JOCO.JOCO_98_20 | DOI Listing |
Gynecol Oncol Rep
February 2025
Department of Ophthalmology and Visual Science, University of Chicago, Chicago, IL, United States.
Introduction: To report a series of patients who developed ocular surface disease related to tisotumab vedotin-tftv (TV), an antibody-drug conjugate (ADC) approved for the treatment of recurrent or metastatic cervical cancer.
Methods: This was a multicenter retrospective chart review study of patients who developed ocular surface disease related to TV between April 1st, 2022 to August 31st, 2023.
Results: Five patients were identified who developed ocular surface disease while on TV.
Cont Lens Anterior Eye
January 2025
Department of Regeneration and Cell Therapy, Andalusian Molecular Biology and Regenerative Medicine Centre (CABIMER), Avda. Américo Vespucio 24, 41092 Seville, Spain.
Purpose: To evaluate the role of contact lenses (CLs) in visual rehabilitation following keratoplasty.
Methods: Four databases, including PubMed, Scopus, Web of Science, and Embase were systematically searched for studies published between January 2010 and July 2023. Visual outcomes, daily wearing duration, subjective comfort, rate and etiology of CL discontinuation, corneal endothelial cell density, central corneal thickness, and complications were extracted.
BMJ Open Ophthalmol
January 2025
Department of Optometry, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia
Objective: This study intended to assess willingness to donate eyes and associated factors among adults in Addis Ababa City, Ethiopia.
Methods And Analysis: This study used a triangulated phenomenological mixed-methods design, involving 1293 adults and eight key informants selected through multistage and purposive sampling. Data collection involved a pretested, semistructured questionnaire for quantitative data and an open-ended guiding questionnaire for qualitative insights.
Cell Death Dis
January 2025
Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Lymphangiogenesis is vital for tissue fluid homeostasis, immune function, and lipid absorption. Abnormal lymphangiogenesis has been implicated in several diseases such as cancers, inflammatory, and autoimmune diseases. In this study, we elucidate the role of tsRNA-0032 in lymphangiogenesis and its molecular mechanism.
View Article and Find Full Text PDFInvest Ophthalmol Vis Sci
January 2025
Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea.
Purpose: Descemet membrane endothelial keratoplasty (DMEK) has emerged as a novel approach in corneal transplantation over the past two decades. This study aims to identify predisposing risk factors for post-DMEK ocular hypertension (OHT) and develop a preoperative predictive model for post-DMEK OHT.
Methods: Patients who underwent DMEK at Gangnam Severance Hospital between 2017 and 2024 were included in the study.
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