Hemodialysis affects myocardial depolarization and repolarization notably lengthening the QT interval. Prolonged QT, in turn, has been a reliable surrogate for higher risk of potentially lethal ventricular arrhythmias. We present an adolescent girl with end-stage kidney disease who consistently developed prolonged QT following hemodialysis sessions. Interestingly, her QT intervals were inversely correlated with her serum magnesium levels. Magnesium supplementation appeared to help reduce the QT prolongation after hemodialysis. Our case shows the potential utility of magnesium as a cardioprotective agent in hemodialysis patients. We recommend that patients undergoing hemodialysis receive frequent electrocardiograms and electrolytes monitoring for tailored electrolytes management to reduce the risk of developing potentially lethal cardiac arrhythmias.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7358902PMC
http://dx.doi.org/10.7759/cureus.9132DOI Listing

Publication Analysis

Top Keywords

magnesium supplementation
8
prolonged hemodialysis
8
hemodialysis
5
magnesium
4
supplementation shortens
4
shortens hemodialysis-associated
4
hemodialysis-associated prolonged
4
hemodialysis myocardial
4
myocardial depolarization
4
depolarization repolarization
4

Similar Publications

Magnesium modulates phospholipid metabolism to promote bacterial phenotypic resistance to antibiotics.

Elife

January 2025

State Key Laboratory of Biocontrol, School of Life Sciences, Guangdong Province Key Laboratory for Pharmaceutical Functional Genes, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Sun Yat-sen University, Guangzhou, China.

Article Synopsis
  • Non-inheritable antibiotic resistance allows bacteria to survive treatment, with exogenous factors like high magnesium playing a significant role.
  • Functional metabolomics show that magnesium affects fatty acid biosynthesis, leading to altered bacterial response to antibiotics based on the balance of saturated and unsaturated fatty acids.
  • Lipid metabolism changes due to magnesium, specifically in glycerophospholipid pathways, enhance bacterial membrane properties that reduce antibiotic uptake and increase resistance.
View Article and Find Full Text PDF

Osteoarthritis (OA) is a significant condition that profoundly impacts synovial joints, including cartilage and subchondral bone plate. Biomaterials that can impede OA progression are a promising alternative or supplement to anti-inflammatory and surgical interventions. Magnesium (Mg) alloys known for bone regeneration potential were assessed in the form of Mg microparticles regarding their impact on tissue regeneration and prevention of OA progression.

View Article and Find Full Text PDF

Magnesium Deficiency: The Insidious Executor of the Liver Disease.

J Am Nutr Assoc

December 2024

Department of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, Tianjin, China.

Magnesium (Mg), which is predominantly present in cells as a micronutrient, is involved in numerous vital physiological processes, such as DNA repair and energy metabolism. Mg deficiency has been reported to contribute toward the advent and progression of a variety of liver diseases; in particular, these two pathological entities may synergistically act. Given the significant impact and increasing burden of liver diseases on global healthcare resources and economic expenditure, it is tempting to manage Mg insufficiency as novel promising therapeutic strategies.

View Article and Find Full Text PDF

Objectives: Hypomagnesemia early diagnosis and consequently early, timely magnesium supplementation is of utmost benefit, but it often goes underdiagnosed. The objective was to show and monitor an intervention to identify hypomagnesemia in patients with arrhythmia.

Methods: A cross-sectional study was designed in the laboratory.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!