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The genetic landscape of Scotland and the Isles.
Proc Natl Acad Sci U S A
September 2019
Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, Scotland;
Britain and Ireland are known to show population genetic structure; however, large swathes of Scotland, in particular, have yet to be described. Delineating the structure and ancestry of these populations will allow variant discovery efforts to focus efficiently on areas not represented in existing cohorts. Thus, we assembled genotype data for 2,554 individuals from across the entire archipelago with geographically restricted ancestry, and performed population structure analyses and comparisons to ancient DNA.
View Article and Find Full Text PDFThe ancient Britons: groundwater fauna survived extreme climate change over tens of millions of years across NW Europe.
Mol Ecol
March 2014
Department of Biological Sciences, Evolutional Biology Group, The University of Hull, Hull, HU6 7RX, UK; Environmental Sciences Research Institute, University of Ulster, Cromore Road, Coleraine, BT52 1SA, Northern Ireland; Biomedical Sciences Research Institute, University of Ulster, Cromore Road, Coleraine, BT52 1SA, Northern Ireland.
Global climate changes during the Cenozoic (65.5-0 Ma) caused major biological range shifts and extinctions. In northern Europe, for example, a pattern of few endemics and the dominance of wide-ranging species is thought to have been determined by the Pleistocene (2.
View Article and Find Full Text PDFIntegration versus apartheid in post-Roman Britain: a response to Thomas et Al. (2008).
Hum Biol
December 2011
School of EIE - Applied Physics, University of South Australia, Mawson Lakes, Adelaide, SA, Australia, 5095.
The genetic surveys of the population of Britain conducted by Weale et al. and Capelli et al. produced estimates of the Germani immigration into Britain during the early Anglo-Saxon period, c.
View Article and Find Full Text PDFGenetic diversity among ancient Nordic populations.
PLoS One
July 2010
Research Laboratory, Faculty of Health Sciences, Institute of Forensic Medicine, University of Copenhagen, Copenhagen, Denmark.
Using established criteria for work with fossil DNA we have analysed mitochondrial DNA from 92 individuals from 18 locations in Denmark ranging in time from the Mesolithic to the Medieval Age. Unequivocal assignment of mtDNA haplotypes was possible for 56 of the ancient individuals; however, the success rate varied substantially between sites; the highest rates were obtained with untouched, freshly excavated material, whereas heavy handling, archeological preservation and storage for many years influenced the ability to obtain authentic endogenic DNA. While the nucleotide diversity at two locations was similar to that among extant Danes, the diversity at four sites was considerably higher.
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