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First Etiologically Confirmed Cases of Mycobacterium Marinum Infection in Bulgaria. | LitMetric

First Etiologically Confirmed Cases of Mycobacterium Marinum Infection in Bulgaria.

Folia Med (Plovdiv)

National Reference Laboratory of Tuberculosis, Sofia, Bulgaria.

Published: June 2020

AI Article Synopsis

  • This study reports the first two confirmed cases of Mycobacterium marinum infection in Bulgaria, a type of non-tuberculous mycobacteria.
  • The infections were identified using specialized media, cultivation techniques, and PCR-based Line Probe Assay at a national laboratory.
  • Both patients worked with fish and water, exhibiting similar symptoms known as "swimming pool" or "fish tank" granuloma, and faced challenges with prolonged treatment involving rifampicin and ethambutol.

Article Abstract

This study aimed to describe the first two microbiologically confirmed cases of cutaneous and soft tissue Mycobacterium marinum infection in Bulgaria. The isolation of the Nontuberculous Mycobacteria (NTM) strains and their species identification was performed at NRL TB, NCIPD using specific media and cultivation conditions, and PCR based Line Probe Assay (LPA) from the positive cultures. The two patients had closely related jobs to fishes and water reservoirs and both of them had a similar clinical manifestation of M. mari-num infection known as "swimming pool" or "fish tank" granuloma. The prolonged specific treatment with at least two-drug combina-tion of rifampicin plus ethambutol and some complications were a big challenge for clinicians as well as the patients.

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Source
http://dx.doi.org/10.3897/folmed.62.e47220DOI Listing

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