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<PubmedArticle><MedlineCitation Status="MEDLINE" Owner="NLM" IndexingMethod="Automated"><PMID Version="1">32660957</PMID><DateCompleted><Year>2021</Year><Month>08</Month><Day>18</Day></DateCompleted><DateRevised><Year>2021</Year><Month>08</Month><Day>18</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">2154-1671</ISSN><JournalIssue CitedMedium="Internet"><Volume>10</Volume><Issue>8</Issue><PubDate><Year>2020</Year><Month>Aug</Month></PubDate></JournalIssue><Title>Hospital pediatrics</Title><ISOAbbreviation>Hosp Pediatr</ISOAbbreviation></Journal><ArticleTitle>Initial Validation of GRASP: A Differential Diagnoses Algorithm for Children With Medical Complexity and an Unknown Source of Pain.</ArticleTitle><Pagination><StartPage>633</StartPage><EndPage>640</EndPage><MedlinePgn>633-640</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1542/hpeds.2019-0322</ELocationID><Abstract><AbstractText Label="OBJECTIVES">Identifying the source of pain for children with medical complexity (MC) is challenging. The purpose of this study was the initial validation of a tool to guide the medical evaluation for identifying the source of pain in children with MC by using differential diagnoses. The tool is entitled Guidelines for Ruling Out and Assessing Source of Pain (GRASP).</AbstractText><AbstractText Label="METHODS">A mixed-methods approach that included expert review, focus groups, Web-based surveys, and a trial of the GRASP was used to determine validity as well as perceived clinical utility.</AbstractText><AbstractText Label="RESULTS">Focus groups were held with 26 inpatient and outpatient clinicians. Participants consistently responded in support of the GRASP. Participants advised several suggestions for tool organization such as designing the tool as a flow diagram. Seven clinicians participated in Web-based surveys and made specific suggestions for making the GRASP more comprehensive. Six participants trialed the GRASP for 14 children with MC and pain of unknown origin. Overall, participants found that the GRASP was a clinically effective tool for guiding medical evaluation.</AbstractText><AbstractText Label="CONCLUSIONS">These results provide preliminary evidence that the GRASP has content and face validity in evaluating the source of pain in children with MC. This tool can be used to systematically guide clinicians through a balanced approach to evaluation with a goal of determining the pain source, preventing harm, and relieving suffering without unnecessary tests.</AbstractText><CopyrightInformation>Copyright &#xa9; 2020 by the American Academy of Pediatrics.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Morse</LastName><ForeName>Brenna L</ForeName><Initials>BL</Initials><AffiliationInfo><Affiliation>Solomont School of Nursing, University of Massachusetts Lowell, Lowell, Massachusetts; brenna_morse@uml.edu.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Solodiuk</LastName><ForeName>Jean C</ForeName><Initials>JC</Initials><AffiliationInfo><Affiliation>Boston Children's Hospital, Boston, Massachusetts; and.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Greco</LastName><ForeName>Christine D</ForeName><Initials>CD</Initials><AffiliationInfo><Affiliation>Boston Children's Hospital, Boston, Massachusetts; and.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mauskar</LastName><ForeName>Sangeeta</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Boston Children's Hospital, Boston, Massachusetts; and.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hauer</LastName><ForeName>Julie</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Boston Children's Hospital, Boston, Massachusetts; and.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Seven Hills Pediatric Center, Groton, Massachusetts.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>07</Month><Day>13</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Hosp Pediatr</MedlineTA><NlmUniqueID>101585349</NlmUniqueID><ISSNLinking>2154-1671</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000465" MajorTopicYN="Y">Algorithms</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002648" MajorTopicYN="N">Child</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D003937" MajorTopicYN="N">Diagnosis, Differential</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D010146" MajorTopicYN="Y">Pain</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010147" MajorTopicYN="N">Pain Measurement</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015203" MajorTopicYN="N">Reproducibility of Results</DescriptorName></MeshHeading></MeshHeadingList><CoiStatement>POTENTIAL CONFLICT OF INTEREST: The authors have indicated they have no potential conflicts of interest to disclose.</CoiStatement></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>7</Month><Day>15</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2021</Year><Month>8</Month><Day>19</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>7</Month><Day>15</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">32660957</ArticleId><ArticleId IdType="doi">10.1542/hpeds.2019-0322</ArticleId><ArticleId IdType="pii">hpeds.2019-0322</ArticleId></ArticleIdList></PubmedData></PubmedArticle></PubmedArticleSet>