AI Article Synopsis

  • This study outlines a simplified two-step technique for transvaginal natural orifice transluminal endoscopic surgery (vNOTES) and provides video evidence from its application.
  • The patients involved were a 27-year-old with ovarian torsion and a 25-year-old with an ectopic pregnancy, both of whom underwent diagnostic and therapeutic procedures via vNOTES.
  • Key steps included creating a colpotomy, confirming the diagnosis using an endoscope, and performing specific surgical interventions while ensuring safety and hemostasis.

Article Abstract

Objective: To describe our simplified two-step technique for transvaginal natural orifice transluminal endoscopic surgery (vNOTES) and to demonstrate the application of the technique.

Design: Step-by-step description of the technique and demonstration of its application using surgical video footage from two different cases.

Setting: Tertiary university hospital.

Patient(s): Patient 1 was a 27-year-old G0P0 woman who presented with right lower quadrant pain. Transvaginal ultrasound scan revealed a right ovarian torsion. Patient 2 was a 25-year-old G3P2 woman. She presented with vaginal bleeding and left lower quadrant pain. Her serum β-human chorionic gonadotropin level was 28,313 U/L, and transvaginal ultrasound scan revealed an ectopic pregnancy in the left tube. The decision to perform vNOTES was made for both patients.

Intervention(s): As the first step, patients underwent diagnostic vNOTES. The patient was placed in lithotomy position under general anesthesia. By use of a 5-mm trocar with autoretracting blade, a colpotomy was performed on the posterior vaginal wall. Pneumoperitoneum was achieved, and the patient was placed in a Trendelenburg position. A 5-mm 30° rigid endoscope was introduced, and the diagnosis was confirmed. After the confirmation of the diagnosis, we proceeded to the second step. The colpotomy was enlarged with blunt dissection by using Metzenbaum scissors. A self-constructed pessary port was placed through the colpotomy, and pneumoperitoneum was achieved. The therapeutic procedure was then performed. Patient 1 underwent ovarian detorsion with a 5-mm laparoscopic grasper. After the ovary was detorsioned, a 5-mm bipolar instrument was used to achieve hemostasis. Patient 2 underwent left salpingectomy with a 5-mm advanced bipolar device. Hemostasis was verified, and the specimen was extracted through the colpotomy. Procedures ended with the closure of colpotomy with running resorbable sutures.

Main Outcome Measure(s): Description of the technique and demonstration of its applicability in two common gynecological emergencies.

Result(s): Both patients were treated successfully by vNOTES. The operating times were 25 minutes and 38 minutes for patient 1 and patient 2, respectively. Patients were discharged on postoperative day 1 without any complications.

Conclusion(s): Our simplified two-step technique described and demonstrated in this video article is a feasible and practical approach to perform vNOTES. The first step allows the confirmation of the diagnosis and facilitates the colpotomy. The use of the self-constructed pessary port enables to perform surgery with already existing equipment without the need for specialized equipment and without increasing the costs.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.fertnstert.2020.05.002DOI Listing

Publication Analysis

Top Keywords

simplified two-step
12
two-step technique
12
technique transvaginal
8
transvaginal natural
8
natural orifice
8
orifice transluminal
8
transluminal endoscopic
8
endoscopic surgery
8
description technique
8
technique demonstration
8

Similar Publications

Integrating advanced Microfluidic lateral flow systems with a finger-prick blood collection cartridge to create an all-in-one platform for point-of-care diagnostics.

Biosens Bioelectron

December 2024

Laboratory of Advanced Biotechnologies for Health Assessments (Lab-HA), Lassonde School of Engineering, York University, Toronto, ON, M3J 1P3 Canada; Department of Electrical Engineering and Computer Science (EECS), Lassonde School of Engineering, York University, Toronto, ON, M3J 1P3, Canada. Electronic address:

Rapid, point-of-care tests are critical for early diagnosis of disease and detection of biological threats. Lateral flow immunoassays (LFIAs) are well-suited for point-of-care testing due to their ease of use and straightforward readout. However, limitations in sensitivity, quantification, and integration into sample-to-result systems indicate the need for further advancements.

View Article and Find Full Text PDF

Isolation of primary keratinocyte stem cells (KSCs) from neonatal mouse epidermis is essential for studying skin physiology and related disorders. Traditional methods often struggle to balance keratinocyte proliferation and differentiation, and although recent advancements using low-calcium culture conditions have improved these techniques, protocols remain scattered. This study presents a streamlined approach to expand mouse KSCs in low-calcium medium (<0.

View Article and Find Full Text PDF

Non-affinity platform for processing knob-into-hole bispecific antibody.

Bioresour Bioprocess

December 2024

Shanghai AsymBio Biotechnology Co., Ltd, Building 8, No.12, Lane 855, Jinzheng Road, Jinshan Industrial Park, Shanghai, China.

Bispecific antibodies hold significant potential as next-generation biotherapeutics owing to their ability to simultaneously bind to two targets. However, the development of bispecific antibodies as biotherapeutics has been hindered by the high levels of byproducts produced, including both high molecular weight and low molecular weight variants. In addition, the inevitable expression of homodimers in host cells presents further obstacles to the commercial development of bispecific antibodies as therapeutics.

View Article and Find Full Text PDF

Silicon nanowires (SiNWs) have garnered considerable attention in the last few decades owing to their versatile applications. One extremely desirable aspect of fabricating SiNWs is controlling their dimensions and alignment. In addition, strict control of surface roughness or diameter modulation is another key parameter for enhanced performance in applications such as photovoltaics, thermoelectric devices, etc.

View Article and Find Full Text PDF

Comparison of conventional and digital impression approaches for edentulous maxilla: clinical study.

BMC Oral Health

November 2024

Department of Prosthodontics, Faculty of Dentistry, Hacettepe University, Ankara, Turkey.

Article Synopsis
  • The study examines new methods for creating tissue-supported complete dentures (TSCDs), highlighting a shift towards faster, comfort-focused, and cost-effective digital and simplified impression techniques, particularly using intraoral scanners (IOS).
  • It involved 15 patients with maxillary complete edentulism and compared various impression methods, including digital options with artificial intelligence support and traditional methods using zinc oxide eugenol and irreversible hydrocolloid.
  • Results indicated digitally captured impressions are comparably effective to conventional methods, particularly in palatal areas, suggesting digital methods could be more widely adopted in clinical practice for improved denture fitting.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!