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Extensive Extramedullary Hematopoiesis in Thalassemia: Soft Tissue Uptake on 99mTc-MDP SPECT/CT. | LitMetric

AI Article Synopsis

  • A 45-year-old man with thalassemia major underwent a bone scan due to generalized bone pain.
  • The imaging revealed multiple elongated soft tissue masses in the ribs and dorsal spine, as well as a large mass in the pelvic region displacing the bladder.
  • A biopsy of the pelvic mass indicated it was extramedullary hematopoiesis, which means blood cell production was occurring outside the bone marrow.

Article Abstract

We report the case of a 45-year-old man with thalassemia major referred for a bone scan as a workup for generalized bone pain. Tc-MDP SPECT CT showed multiple elongated soft tissue masses along the inner aspects of ribs and along both sides of dorsal spine with calcification and mild tracer uptake. There was also a large lobulated presacral soft tissue mass displacing the bladder and involving the adjacent pelvic bone. Biopsy of mildly avid tracer uptake in pelvic soft tissue mass was extramedullary hematopoiesis confirmed by biopsy.

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Source
http://dx.doi.org/10.1097/RLU.0000000000003191DOI Listing

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