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| http://dx.doi.org/10.1016/j.accpm.2020.06.011 | DOI Listing |
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Lung recruitment with HFOV versus VTV/AC in preterm infants with RDS.
BMC Pediatr
December 2024
Pediatrics and Neonatology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Objectives: To compare the effect of lung recruitment using high frequency ventilation versus volume targeted ventilation on duration of intubation as well as its effect on lung inflammation in preterm infants with respiratory distress syndrome.
Methods: The study was conducted on a total of 40 preterm infants, 34 weeks gestational age or less, having RDS that needed intubation and mechanical ventilation within the first 72 h after their birth at the NICU of Mansoura University Children's Hospital during the period from July 2020 to July 2022. Infants included were randomly assigned into two groups, Group A who were subjected to LRM using HFOV (20 cases) and Group B who were subjected to LRM using VTV/AC (20 cases).
Strategies to innovate emergency care of status epilepticus.
Neurotherapeutics
December 2024
Department of Neurology and Neuroscience Brain Institute University of Virginia, School of Medicine, Health Sciences Center, Box 801330, Charlottesville, VA 22908-1330, USA. Electronic address:
Generalized Convulsive status epilepticus (SE) is a neurological emergency because prolonged convulsions can cause respiratory compromise and neuronal injury. Compromised GABA-mediated inhibition is a defining feature of SE, and many current therapies are benzodiazepines, which are allosteric modulators of GABA-A receptors. Many patients with medically refractory epilepsy are at risk for SE.
View Article and Find Full Text PDFComprehensive surgical management of a severe 270-degree circumferential penetrating neck injury from an industrial accident: a case report.
J Surg Case Rep
December 2024
Anesthesia Techniques Department, College of Health and Medical Techniques, Al-Mustaqbal University, Najaf Road, 51001, Hilla, Iraq.
Penetrating neck injury (PNI), involving disruption of the platysma muscle, accounts for 10% of trauma cases and poses significant morbidity and mortality risks. This case report details the management of a 45-year-old male who sustained a 270-degree circumferential neck incision from an industrial accident. The patient presented with a deep neck laceration, severe blood loss, and hypovolemic shock.
View Article and Find Full Text PDFDelta shock index predicts injury severity, interventions, and outcomes in trauma patients: A 10-year retrospective observational study.
World J Crit Care Med
December 2024
Department of Surgery, Trauma Surgery Section, Hamad Medical Corporation, Doha 3050, Qatar.
Background: Most trauma occurs among young male subjects in Qatar. We examined the predictive values of the delta shock index (DSI), defined as the change in the shock index (SI) value from the scene to the initial reading in the emergency unit (, subtracting the calculated SI at admission from SI at the scene), at a Level 1 trauma center.
Aim: To explore whether high DSI is associated with severe injuries, more interventions, and worse outcomes [, blood transfusion, exploratory laparotomy, ventilator-associated pneumonia, hospital length of stay (HLOS), and in-hospital mortality] in trauma patients.
Nasal continuous positive airway pressure immediately after extubation for preventing morbidity in preterm infants.
Cochrane Database Syst Rev
October 2024
Newborn Research Centre and Neonatal Services, The Royal Women's Hospital, Melbourne, Australia.
Article Synopsis
- Preterm infants often face the risk of respiratory failure after being extubated from invasive ventilation, and this can occur due to issues like apnoea and hypoxia. Traditionally, they were extubated to head box oxygen or low-flow nasal cannulas, but non-invasive support such as nasal continuous positive airway pressure (NCPAP) may enhance extubation success by stabilizing the airway and improving lung function.
- The objective of the reviewed study is to find out if using NCPAP right after extubation can lower the occurrence of reintubation and the need for further ventilatory support in preterm infants, while ensuring there are no significant negative side effects.
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