Thoracic aortic aneurysms present significant challenges to clinicians, especially due to their complex nature and an evolving understanding of the safest and most effective ways to manage this condition in the perioperative setting. Thoracic aortic aneurysms have a prevalence rate of 1.3-8.9% in men and 1.0-2.2% in women, and they are estimated to affect more than five per 100,000 person-years. This is notable because the complications of thoracic aortic aneurysms can be catastrophic. The current understanding of the optimal intraoperative management of thoracic aortic aneurysms is changing, as more evidence becomes available regarding lung protective ventilation and its role in enhancing patient safety and wellbeing. This review strives to provide a brief historical understanding of thoracic aortic aneurysms and highlight some of the key discoveries and advances in the management of this condition. This review then describes an overview of the general anaesthetic principles associated with thoracic aortic aneurysms, including ventilatory modalities and how these impact a patient's physiology and intraoperative haemodynamics. A brief discussion on one-lung ventilation is then provided, drawing from current literature in the field, to describe the most up-to-date management of thoracic aortic aneurysms.
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http://dx.doi.org/10.1177/1750458920936064 | DOI Listing |
PLoS One
January 2025
Department of Vascular Surgery, Charm Vascular Clinic, Seoul, Republic of Korea.
Background: Abdominal aortic aneurysm (AAA) is more common in Non-small cell lung cancer (NSCLC) patients. Considering that ruptured AAA is potentially fatal, timely management of AAA would result in long-term survival benefits. We assess the prevalence and characteristics of AAA in resectable NSCLC patients who would benefit from AAA surveillance.
View Article and Find Full Text PDFExpert Rev Med Devices
January 2025
Long Beach Memorial Medical Center, MemorialCare Heart & Vascular Institute.
Introduction: Since the mid-1900s, techniques in the repair of aortic arch and thoracoabdominal aortic pathologies have drastically evolved. Open aortic surgical repair was once the sole option for both simple and complex aneurysmal degeneration. Today, a number of minimally invasive and hybrid approaches are now available to assist both the surgeon and patient in tackling this challenging problem.
View Article and Find Full Text PDFBiomech Model Mechanobiol
January 2025
CNRS, LaMCoS, UMR5259, INSA Lyon, 69621, Villeurbanne, France.
Predicting the evolution of ascending aortic aneurysm (AscAA) growth is a challenge, complicated by the intricate interplay of aortic geometry, tissue behavior, and blood flow dynamics. We investigate a flow-structural growth and remodeling (FSG) model based on the homogenized constrained mixture theory to simulate realistic AscAA growth evolution. Our approach involves initiating a finite element model with an initial elastin insult, driven by the distribution of Time-Averaged Wall Shear Stress (TAWSS) derived from computational fluid dynamics simulations.
View Article and Find Full Text PDFCardiovasc Res
January 2025
Department of Cardiac Surgery, Medical University of Vienna, Währinger Gürtel 18-20, Vienna A-1090, Austria.
J Vasc Surg Cases Innov Tech
February 2025
Department of Vascular and Endovascular Surgery, Beth Israel Deaconess Hospital, Boston, MA.
Iliac artery aneurysms commonly present in patients with associated aortic disease. Isolated aneurysms of the iliac arteries are uncommon, mostly involving the common iliac artery. Isolated external iliac artery aneurysms are the rarest iliac aneurysmal pathology.
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