A coding-complete genome sequence of a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) isolate was revealed. The sample for the virus was isolated from a female patient from Dhaka, Bangladesh, suffering from coronavirus disease-2019 (COVID-19).

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348026PMC
http://dx.doi.org/10.1128/MRA.00626-20DOI Listing

Publication Analysis

Top Keywords

coding-complete genome
8
genome sequence
8
sars-cov-2 isolate
8
sequence sars-cov-2
4
isolate bangladesh
4
bangladesh sanger
4
sanger sequencing
4
sequencing coding-complete
4
sequence severe
4
severe acute
4

Similar Publications

Unlabelled: Plant-infecting alphaflexiviruses cause moderate to severe diseases in economically important crops worldwide. In the present study, we identified nine putative novel alphaflexiviruses in nine plant species by exploring the publicly available plant transcriptome data in Sequence Read Archive (SRA) database. Coding-complete genomes of all the identified viruses were recovered and contained five to six open reading frames (ORFs).

View Article and Find Full Text PDF

Sequencing RNA from old, dried specimens reveals past viromes and properties of long-surviving RNA.

bioRxiv

October 2024

Center for Vector-Borne and Infectious Diseases, Department of Microbiology, Immunology, and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, USA.

Recovery of virus sequences from old samples provides an opportunity to study virus evolution and reconstruct historic virus-host interactions. Studies of old virus sequences have mainly relied on DNA or on RNA from fixed or frozen samples. The millions of specimens in natural history museums represent a potential treasure trove of old virus sequences, but it is not clear how well RNA survives in old samples.

View Article and Find Full Text PDF

C→U transition biases in SARS-CoV-2: still rampant 4 years from the start of the COVID-19 pandemic.

mBio

December 2024

Nuffield Department of Medicine, Peter Medawar Building for Pathogen Research, University of Oxford, Oxford, United Kingdom.

Unlabelled: The evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the pandemic and post-pandemic periods has been characterized by rapid adaptive changes that confer immune escape and enhanced human-to-human transmissibility. Sequence change is additionally marked by an excess number of C→U transitions suggested as being due to host-mediated genome editing. To investigate how these influence the evolutionary trajectory of SARS-CoV-2, 2,000 high-quality, coding complete genome sequences of SARS-CoV-2 variants collected pre-September 2020 and from each subsequently appearing alpha, delta, BA.

View Article and Find Full Text PDF

Coding complete genomes of an iridovirus (194,403 nts) and two parvoviruses (4,689, 3,764 nts) were identified in social spiders (). The iridovirus and one of the parvovirus are most closely related to those from house crickets (), whereas the other is most closely related to one from a social spider.

View Article and Find Full Text PDF

Sequencing of historic samples provides complete coding sequences of chicken calicivirus from the United States.

Microbiol Resour Announc

October 2024

Exotic and Emerging Avian Viral Disease Research Unit, Southeast Poultry Research Laboratory, U.S. National Poultry Research Center, ARS, USDA, Athens, Georgia, USA.

Here, we report the coding-complete genomic sequences of two chicken caliciviruses from US poultry flocks in 2003 and 2004. They show the same genomic organization as that of other members of the genus and have the highest nucleotide identity (~88%) with strains from clinically normal chickens from Germany in 2004 and Netherlands in 2019.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!