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C60 fullerene improves the contractile activity of the injured rat muscle gastrocnemius.
Nanotechnology
December 2024
Institute of Chemistry and Biotechnology, Technical University of Ilmenau, Weimarer Str. 25, Ilmenau, 98693, GERMANY.
The powerful antioxidant properties of C60 fullerenes have been widely used in biomedical nanotechnology. Owing to the negative effects of free radicals in oxidative stress processes, antioxidants are required to protect injured muscles. Here, the effect of water-soluble C60 fullerenes (daily oral dose 1 mg/kg) on the process of restoration of contractile activity of skeletal muscle of rats (muscle gastrocnemius) 15 days after the initiation of open trauma of different severity was studied for the first time.
View Article and Find Full Text PDFThe measurement of phenols with graphitic carbon fiber microelectrodes and fast-scan cyclic voltammetry.
Nanotechnology
December 2024
Chemistry, American University, 4400 Massachusetts Ave NW, Washington, Washington, District of Columbia, 20016-8002, UNITED STATES.
A phenol contains a six-membered, conjugated, aromatic ring that is bound to a hydroxyl group. These molecules are important in biomedical studies, aromatic food preparation, and petroleum engineering. Traditionally, phenols have been measured with several analytical techniques such as UV-VIS spectroscopy, fluorescence, liquid chromatography, and mass spectrometry.
View Article and Find Full Text PDFImpaired Wnt/Planar Cell Polarity Signaling in Yellow Nail Syndrome.
Ann Intern Med
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The Genetics Institute and Genomics Center, Tel Aviv Sourasky Medical Center, and School of Medicine, Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel (H.B.F.).
Background: Yellow nail syndrome (YNS) is a rare disorder characterized by a triad of yellow dystrophic nails, lymphedema, and chronic lung disease. Most patients present in adulthood, with only a few congenital or familial cases described. The cause of YNS remains largely unknown, although defects in lymphatic vessel development are suggested to play a significant role.
View Article and Find Full Text PDFIdentifying the Relative Importance of Factors Influencing Medication Compliance in General Patients Using Regularized Logistic Regression and LightGBM: Web-Based Survey Analysis.
JMIR Form Res
December 2024
Division of Drug Informatics, Faculty of Pharmacy and Graduate School of Pharmaceutical Sciences, Keio University, Tokyo, Japan.
Background: Medication compliance, which refers to the extent to which patients correctly adhere to prescribed regimens, is influenced by various psychological, behavioral, and demographic factors. When analyzing these factors, challenges such as multicollinearity and variable selection often arise, complicating the interpretation of results. To address the issue of multicollinearity and better analyze the importance of each factor, machine learning methods are considered to be useful.
View Article and Find Full Text PDFThe Use of "Cancer Ratio" in Differentiating Malignant and Tuberculous Pleural Effusions: Protocol for a Prospective Observational Study.
JMIR Res Protoc
December 2024
Department of Community Medicine, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Karnataka, Manipal, 576 104, India.
Background: Differentiating between tuberculosis and malignancy as the cause of an exudative lymphocyte predominant pleural effusion is difficult due to similarities in the cellular and biochemical characteristics of the pleural fluid in both conditions. Microbiological tests in tubercular pleural effusions have a poor diagnostic yield, and the long turnaround time for results prevents an early diagnosis. The diagnosis of malignant pleural effusion (MPE) is hampered by a variable yield of pleural fluid cytology and closed pleural biopsy and the fact that thoracoscopy may not be readily available or feasible in each patient.
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