Objectives: To analyze CD35/CD89 expression ratio on the surface of neutrophils as an early detection marker for S-ECC.
Materials And Methods: Saliva was collected from 4- to 6-year-old kindergarten students. Salivary neutrophils were obtained by instructing the subjects to rinse their mouth with 1 mL of sterile 1.5% NaCl for 30 seconds before expectorating it into a sterile glass. The expression of CFSECD35 and CFSECD89was measured and analyzed using flow cytometry.
Results: The expression of CFSECD89 in the caries-free group (2.46 ± 0.39) was significantly lower than that in the S-ECC group (3.41 ± 1.11), with a -value of 0.0001, while the expression of CFSECD35 in the caries-free group was (2.35 ± 0.56) compared with (1.54 ± 0.35) ( = 0.0001) in the S-ECC group.
Conclusions: The expression ratio of CFSECD89 and CFSECD35constitutes a marker for S-ECC.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7440938 | PMC |
| http://dx.doi.org/10.1055/s-0040-1713704 | DOI Listing |
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