AI Article Synopsis
- COVID-19, caused by the SARS-CoV-2 virus, was first identified in December 2019 in Wuhan, China, rapidly leading to a global pandemic with over 350,000 deaths and 5 million infections within six months.
- The quick sequencing of the virus's genome and production of testing kits were not enough to ensure effective diagnosis and treatment, emphasizing the need for a deeper understanding of the disease's pathology.
- Histotechnology has been pivotal in studying COVID-19 pathology, with significant findings emerging from early postmortem biopsies, indicating that more molecular and immunohistochemical research will be essential for advancing our comprehension of the disease.
Article Abstract
COVID-19 disease in humans, caused by the novel SARS-CoV-2 virus, was first reported in the city of Wuhan, China in December 2019. This disease has quickly developed into a global pandemic, resulting in over 350,000 deaths worldwide and over 5 million confirmed infections in a matter of 6 months. Although the genome of this novel viral RNA was sequenced quickly and testing kits were manufactured to assist in combatting COVID-19, the diagnosis and treatment will remain relatively unsuccessful until the pathology of this disease is fully understood. Histotechnology plays an important role in understanding the pathology of many diseases, including COVID-19. The first postmortem biopsy of a COVID-19 patient was collected on 27 January 2020, and the pathology finding was published in mid-February 2020. Since then, more studies have been published in scientific literatures as the global outbreak continues. This mini-review summarizes the published articles in which histotechnology aspects were utilized with the intent to understand the pathology of COVID-19. In addition, it is anticipated there will be more molecular and immunohistochemical studies to further understand the mechanism of the disease in the near future.
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| http://dx.doi.org/10.1080/01478885.2020.1779484 | DOI Listing |
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