As countries move towards achieving universal health coverage, efforts to engage all care providers have gained more significance. Over a third of people estimated to have developed TB in 2018 were not detected and notified by national TB programs (NTPs). This gap is more pronounced in countries with large private sectors, especially those with a high burden of TB. Health care providers outside the scope of NTPs, including the private and informal sector, are often the first point of care for TB patients. However, these providers are not fully engaged despite evidence from country experiences and projects that demonstrate increased detection and good treatment outcomes through publicprivate mix (PPM) approaches. While there are often concerns about quality of care in public facilities, there is also increasing evidence that quality of TB care in the private sector falls short of international standards in many places and urgently needs improvement. Failure to engage the full range of health care providers for TB has serious consequences in terms of access to quality care, resulting in increased transmission as a result of delayed diagnosis and treatment; excess mortality and morbidity as a result of inappropriate treatment; and increased drug resistance as a result of incomplete treatment. Recent attention to this issue has led to significant increases in private TB notifications, especially in India, Indonesia and the Philippines, but the gap between notification and the extension of quality program services for provision of treatment and care appears to be growing.
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http://dx.doi.org/10.1016/j.jctube.2020.100171 | DOI Listing |
J Neural Transm (Vienna)
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Laboratory of Biological Psychiatry, Institute of Mental Health, Tianjin Anding Hospital, Mental Health Center of Tianjin Medical University, 13 Liulin Road, Tianjin, 300222, China.
Bipolar disorder (BD) frequently coexists with anxiety disorders, creating complex challenges in clinical therapy and management. This study investigates the prevalence, prognostic implications, and treatment strategies for comorbid BD and anxiety disorders. High comorbidity rates, particularly with generalized anxiety disorder, underscore the necessity of thorough clinical assessments to guide effective management.
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Cosmetics Europe, Brussels, Belgium.
Grouping of chemicals has been proposed as a strategy to speed up the screening and identification of potential substances of concern among the broad chemical universe under REACH. Such grouping is usually based on shared structural features and should only be used for the prioritization objectives. However, additional considerations (as well as structural similarity) are needed, e.
View Article and Find Full Text PDFSci Rep
January 2025
Center of Excellence for Antimicrobial Resistance and Stewardship, Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, 10330, Thailand.
The pathogenic oomycete Pythium insidiosum causes a fatal infectious illness known as pythiosis, impacting humans and certain animals in numerous countries in the tropics and subtropics. Delayed diagnosis is a primary factor contributing to the heightened morbidity and mortality associated with the disease. Several new serodiagnostic methods have been developed to improve the identification of pythiosis.
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Sarcoma Unit, Department of Surgery, University Medical Center and Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
Purpose: The management of soft tissue sarcoma (STS) at reference centers with specialized multidisciplinary tumor boards (MTB) improves patient survival. The German Cancer Society (DKG) certifies sarcoma centers in German-speaking countries, promoting high standards of care. This study investigated the variability in treatment recommendations for localized STS across different German-speaking tertiary sarcoma centers.
View Article and Find Full Text PDFEur J Hum Genet
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Murdoch Children's Research Institute, Melbourne, VIC, Australia.
People from refugee and migrant backgrounds often face poor experiences and outcomes in healthcare, and genetic healthcare is no exception. Understanding whether and how these health inequities manifest is an important step towards equitable perinatal genetic screening for genetic or chromosomal conditions (offered preconception, prenatally, or during the newborn period). A scoping review was conducted to review international evidence of perceptions and experiences of perinatal genetic screening for people from migrant and refugee backgrounds.
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