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Comment on Borșa et al. Developing New Diagnostic Tools Based on SERS Analysis of Filtered Salivary Samples for Oral Cancer Detection. 2023, , 12125.
Int J Mol Sci
December 2024
Laser and Biotechnical Systems Department, Samara National Research University, Moskovskoe Shosse 34, 443086 Samara, Russia.
This comment discusses a recent research paper on the classification of saliva samples with SERS by Borsa et al. The authors suggested utilizing PCA-LDA to detect oral cancer and claimed to achieve an accuracy of up to 77%. Despite the high prediction capability of the proposed approach, the demonstrated findings could be treated as unclear due to possible overestimation of the proposed classification models.
View Article and Find Full Text PDFShould we pay more attention to the potential link between and esophageal cancer in Asian countries.
World J Gastroenterol
December 2024
Department of Gastroenterology, The First Affiliated Hospital of University of Science and Technology of China, Hefei 230001, Anhui Province, China.
The presence of () infection has been indicated to have a protective influence on esophageal cancer (EC) in some studies, but its specific impact on the risk of esophageal squamous cell carcinoma and esophageal adenocarcinoma remains inconclusive. This manuscript comment addresses the recent study by López-Gómez . Despite it was a retrospective observational study without a control group, this study revealed a notably low prevalence of infection among EC patients, indicating a potential association between and EC in Spain.
View Article and Find Full Text PDFHow Do Australians Manage Diagnostic Testing Risks? Focus Groups Linked to a Model of Behaviour Change.
Health Expect
October 2024
School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
Background: Diagnostic tests carry significant risks, and communications are needed to help lay people consider these. The development of communications has been hindered by poor knowledge about how lay people understand and negotiate testing risks. We examined lay Australians' perceptions of diagnostic testing risks and how these risks are managed.
View Article and Find Full Text PDFTaking stock of global fisheries.
Science
August 2024
Sea Around Us, Institute for the Oceans and Fisheries, University of British Columbia, Vancouver, BC, Canada.
Current stock assessment models overestimate productivity and recovery trajectory.
View Article and Find Full Text PDFResponse to Biophysical Journal comment to the editor by Skóra regarding the article entitled: Vast heterogeneity in cytoplasmic diffusion rates revealed by nanorheology and Doppelgänger simulations.
Biophys J
August 2024
Department of Cell and Tissue Biology, University of California, San Francisco, San Francisco, California.
In a Comment to the Editor, Skóra raises a concern that the modeling framework implemented in Garner et al. (Biophysical Journal, 2023) neglects a potentially important term in the Brownian dynamics simulation of diffusion. Omission of this diffusivity gradient term may lead to an underestimation of the mean and overestimation of the variance of the cytoplasmic viscosity.
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