A device called FeelBreathe (FB) was designed, developed, and patented for inspiratory muscle training. The main aim was to determine the acute responses on lung ventilation, gas exchange, and heart rate during exercise in patients with chronic obstructive pulmonary disease (COPD) with and without the use of FB. In this study, a randomized cross-over trial was performed with 18 men diagnosed with COPD (FEV between 30% and 70% of its predicted value). Each participant randomly conducted two trials with 30 min of rest between them with the same protocol on a treadmill for 10 min at a constant rate of 50% of VO. Each test was performed randomly and in a crossover randomized design in two different conditions: (1) oronasal breathing; and (2) nasal breathing with FB (nasal ventilatory flow restriction device). It was observed that FB had positive effects on dynamic hyperinflation, breathing pattern, and breathing efficiency, with higher expiratory and inspiratory time. Despite these differences, blood oxygen saturation percentage, oxygen uptake, and heart rate showed a similar response for both conditions during exercise. The results suggest that exercise performed with FB improved ventilatory responses compared to the oronasal mode in COPD patients. This new tool could be used during most daily tasks and exercise programs.
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http://dx.doi.org/10.3390/ijerph17134876 | DOI Listing |
Nat Commun
January 2025
Institute of Physiology and Pathophysiology, Medical Faculty, Heidelberg University, Heidelberg, Germany.
Complex experimental protocols often require multi-modal data acquisition with precisely aligned timing, as well as state- and behavior-dependent interventions. Tailored solutions are mostly restricted to individual experimental setups and lack flexibility and interoperability. We present an open-source, Linux-based integrated software solution, called 'Syntalos', for simultaneous acquisition and synchronization of data from an arbitrary number of sources, including multi-channel electrophysiological recordings and different live imaging devices, as well as closed-loop, real-time interventions with different actuators.
View Article and Find Full Text PDFACS Appl Mater Interfaces
January 2025
Institute of High Pressure Physics, Polish Academy of Sciences, Warsaw 01-142, Poland.
Ultrasmall micro-light-emitting diodes (μLEDs), sized below 10 μm, are indispensable to create the next-generation augmented and virtual reality (AR/VR) devices. Their high brightness and low power consumption could not only enhance the user experience by providing vivid and lifelike visuals but also extend device longevity. However, a notable challenge emerges: a decrease in efficiency with a reduced size.
View Article and Find Full Text PDFData Brief
February 2025
Interdisciplinary Laboratory for Research in Education, EA7483, University of New Caledonia, Noumea, New Caledonia.
This paper presents a dataset related to the physical activity behavior of 206 adolescents (107 females and 99 males) from 11 to 16 years old and 25 adults (13 females and 12 males) living in rural (77 adolescents and 15 adults) and urban (129 adolescents and 10 adults) parts of New Caledonia, an archipelago of the South Pacific. Physical behavior was assessed through 60-Hz triaxial GENEActiv accelerometers worn for 5 to 7 consecutive days between July 2018 and April 2019. Participants were randomly recruited at school and trained staff fitted the devices on the nondominant wrist, at which time all were reminded of the expectations while wearing the device.
View Article and Find Full Text PDFResearch (Wash D C)
January 2025
School of Physics & Wuhan National Laboratory for Optoelectronics (WNLO), Huazhong University of Science and Technology (HUST), Wuhan 430074, China.
After years of research and development, flexible sensors are gradually evolving from the traditional "electronic" paradigm to the "ionic" dimension. Smart flexible sensors derived from the concept of ion transport are gradually emerging in the flexible electronics. In particular, ionic hydrogels have increasingly become the focus of research on flexible sensors as a result of their tunable conductivity, flexibility, biocompatibility, and self-healable capabilities.
View Article and Find Full Text PDFJ Colloid Interface Sci
January 2025
Institute of Optoelectronic Materials and Devices, College of Optical and Electronic Technology, China Jiliang University, Hangzhou 310018 PR China. Electronic address:
Red light emitting perovskite quantum dot (PQD) glass, with narrow-band emission and excellent stability, holds great potential for applications in liquid crystal displays. However, its low photoluminescence quantum yield (PLQY) remains the biggest obstacle limiting its practical application. Additionally, the mechanism behind the enhancement of the PLQY is not well understood, which restricts the further improvement of the PLQY in red light emitting PQD glass.
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