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| http://dx.doi.org/10.1002/jmv.26272 | DOI Listing |
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Nicking Activity of M13 Bacteriophage Protein 2.
Int J Mol Sci
January 2025
Department of Biomedical Engineering, Faculty of Engineering and Natural Sciences, Acibadem Mehmet Ali Aydinlar University, 34752 Istanbul, Türkiye.
Gene II Protein (Gp2/P2) is a nicking enzyme of the M13 bacteriophage that plays a role in the DNA replication of the viral genome. P2 recognizes a specific sequence at the f1 replication origin and nicks one of the strands and starts replication. This study was conducted to address the limitations of previous experiments, improve methodologies, and precisely determine the biochemical activity conditions of the P2 enzyme in vitro.
View Article and Find Full Text PDFInclusive Education for University Students With and Without Intellectual Disabilities: Effectiveness of an Anti-Stigma Intervention.
J Appl Res Intellect Disabil
January 2025
Department of Educational Theory and Social Pedagogy, UNED (Spain' Open University), Madrid, Spain.
Background: This study examines stigma and self-stigma towards individuals with intellectual disabilities among university students, focusing on cognitive, emotional and behavioural dimensions. It highlights the negative impact on social inclusion and the importance of educational interventions.
Methods: A quantitative pre-/post-test design with a control group assessed stigma towards intellectual disabilities.
Illusory implications: incidental exposure to ideas can induce beliefs.
R Soc Open Sci
January 2025
Arizona State University, Glendale, AZ, USA.
Numerous psychological findings have shown that incidental exposure to ideas makes those ideas seem more true, a finding commonly referred to as the 'illusory truth' effect. Under many accounts of the illusory truth effect, initial exposure to a statement provides a metacognitive feeling of 'fluency' or familiarity that, upon subsequent exposure, leads people to infer that the statement is more likely to be true. However, genuine beliefs do not only affect truth judgements about individual statements, they also imply other beliefs and drive decision-making.
View Article and Find Full Text PDFFeasibility of implementing family-integrated newborn care for hospitalised preterm and low birthweight infants in newborn care units of Ethiopia: a mixed-methods design.
BMJ Open
January 2025
Faculty of Health Sciences, University of Stavanger, Stavanger, Norway.
Objective: To evaluate the feasibility of implementing family-integrated newborn care (FINC) for hospitalised preterm and low birthweight infants in Ethiopia. Despite the WHO's call for family engagement in newborn care, evidence of the feasibility of implementation remains scarce.
Design: An observational feasibility study employing a mixed-methods design comprising a quantitative cross-sectional survey among 157 healthcare providers (HCPs) and a qualitative Participatory Rural Appraisal.
DepRescribing inapprOpriate Proton Pump InhibiTors (DROPIT): study protocol of a cluster-randomised controlled trial in Swiss primary care.
BMJ Open
January 2025
Institute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland
Objectives: Proton pump inhibitors (PPIs) are widely prescribed medications and commonly used for the treatment of gastric acid-related disorders. Nevertheless, PPIs are often overused leading to potential adverse effects and unnecessary healthcare costs. Deprescribing strategies have emerged to safely reduce or substitute inappropriate PPIs and optimise patient care in an evidence-based manner.
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