Francisella noatunensis subsp. orientalis (Fno) and Ichthyophthirius multifiliis (Ich) are deadly infectious pathogens in farmed tilapia, particularly during cold season when the water temperature drops to under 25 °C. We hypothesized that infection of the ectoparasite Ich might enhance susceptibility of hybrid red tilapia (Oreochromis sp.) to the facultative intracellular bacterium Fno. To prove the hypothesis, the experiment was designed as follows. Hybrid red tilapia naturally infected by Ich at 9 ± 6 theronts/fish gills and 4 ± 3 theronts/fish skin were distributed into 5 distinct groups exposed to different concentrations of Fno. In parallel, the same number of Ich-free tilapia were challenged to only Fno in the same manner. The results showed that cumulative mortality in the Fno single infection with 2.88 × 10 CFU mL of water was 25 ± 7%, whereas 100% mortality was found in the coinfection treatment at dose of 1.93 × 10 CFU mL of water. No mortality was observed in both control groups (Ich-infected and Ich-free fish). The coinfected fish revealed typical clinical signs and histopathological manifestations of francisellosis and ichthyophthiriasis. This study revealed synergistic effect of the Ich and Fno infection in hybrid red tilapia leading to the exacerbated mortality. Thus, farming management of fish to be free from the Ich ectoparasite might reduce risk of francisellosis and probably other bacterial diseases in farmed tilapia.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.micpath.2020.104369 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Multiplex-PCR technique to predict polymorphic antigens - M, N, S and s - and associations between their alleles and Mi-associated hybrid glycophorins.
Sci Rep
January 2025
Graduate Program in Medical Technology, Faculty of Allied Health Sciences, Thammasat University, Pathumthani, 12120, Thailand.
Serological typing of MNS polymorphic antigens - M, N, S and s - remains a fundamental technique in transfusion medicine and prenatal care, providing essential information for matching blood donors and recipients and managing haemolytic disease. Although this method is well proven and routinely used, it is not a comprehensive solution, as it has several weaknesses. Alternatively, multiplex polymerase chain reaction (PCR) is a commonly used genotyping tool due to its potency and ability to amplify several DNA targets simultaneously in a single reaction.
View Article and Find Full Text PDFHigh-Efficiency, Long-Lifetime and Color-Tunable Hybrid WOLEDs Using a Platinum Complex with Voltage-Dependent Monomer and Aggregate Emission.
Adv Sci (Weinh)
January 2025
State Key Laboratory of Synthetic Chemistry, Department of Chemistry, HKU-CAS Joint Laboratory on New Materials, The University of Hong Kong, Pokfulam Road, Hong Kong SAR, 999077, P. R. China.
Color-tunable white organic light-emitting diodes (CT-WOLEDs) have attracted widespread attention given their large color variation to meet the different daily scenarios from the perspective of circadian rhythm. However, most reported CT-WOLEDs, especially the tri-color devices, exhibit poor performances and sophisticated structures. Here, a simple structure tri-color CT-WOLED is demonstrated that simultaneously exhibits high efficiency, ultralong operation lifetime, and wide color-tunable range for dynamic sunlight emulation.
View Article and Find Full Text PDFSpatial and Temporal Regulation of Flower Coloration in Cymbidium lowianum.
Plant Cell Environ
January 2025
Key Laboratory of Economic Plants and Biotechnology, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, Yunnan, China.
Flower color is a crucial trait that attracts pollinators and determines the ornamental value of floral crops. Cymbidium lowianum, one of the most important breeding parent of Cymbidium hybrids, has two flower morphs (normal and albino) that differ in flower lip color. However, the molecular mechanisms underlying flower color formation in C.
View Article and Find Full Text PDFEnhancing RT-PCR Throughput and Sensitivity through Large-Scale Sample Pooling Using a Nano-Hybrid Membrane.
Adv Sci (Weinh)
January 2025
Department of Electrical Engineering, Kwangwoon University, Seoul, 01897, Republic of Korea.
During the pandemic surge, including SARS-CoV-2 and influenza, pooling samples emerged as an efficient strategy to identify infected individuals in large groups. While pooling enhances RT-PCR throughput, reducing costs and resources, it dilutes positive samples with negative ones, lowering sensitivity and increasing false negatives. This study proposes a new method to address the trade-off between pool sizes and RT-PCR accuracy.
View Article and Find Full Text PDFSynthesis and antibacterial evaluation of quinoline-sulfonamide hybrid compounds: a promising strategy against bacterial resistance.
RSC Adv
January 2025
Department of Chemistry, Jamia Millia Islamia Jamia Nagar New Delhi-110025 India
Antibiotic-resistant bacteria are a serious global health threat, making infections harder to treat and increasing medical costs and mortality rates. To combat resistant bacterial strains, a series of compounds (QS1-12) were synthesized with an excellent yield of 85-92%. Initial assessments of these analogues as potential antibacterial agents were conducted through a preliminary screening against a panel of diverse bacterial strains.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!