Objectives: To compare the asphericity and higher-order aberration (HOA) outcomes of single-step transepithelial photorefractive keratectomy (tPRK) and conventional alcohol-assisted PRK (aaPRK) in patients with myopia and myopic astigmatism.
Materials And Methods: Of the 108 eyes of 54 patients enrolled in the study, tPRK was performed on 54 (50%) eyes and aaPRK was performed on 54 (50%) eyes. The following parameters were compared: corrected distance visual acuity (CDVA), spherical equivalent (SE), flat and steep keratometry, intraocular pressure, central corneal thickness, asphericity, and HOAs including horizontal and vertical coma, horizontal and vertical trefoil, spherical aberration, second-order vertical coma, and aberration coefficient.
Results: The demographic and baseline characteristics were similar between the two groups (p>0.05, for all). The aberration coefficient value was significantly lower in patients treated with aaPRK compared to patients treated with tPRK at postoperative 3 months, 6 months, and 1 year (p=0.022, p=0.019, and p=0.017, respectively). Differences in the other variables were statistically insignificant (p>0.05 for all).
Conclusion: Both tPRK and aaPRK procedures obtain similar postoperative CDVA, SE, asphericity, and HOA outcomes, except the aberration coefficient value.
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http://dx.doi.org/10.4274/tjo.galenos.2019.14554 | DOI Listing |
J Ophthalmol
November 2024
Department of Ophthalmology, Queensland Eye Institute, South Brisbane, Queensland, Australia.
To report the refractive outcomes of StreamLight transepithelial photorefractive keratectomy (PRK). A retrospective case series was conducted which included a total of 205 eyes of 109 patients who underwent StreamLight transepithelial PRK using the Alcon Wavelight EX500 excimer laser. All eyes had myopia or myopic astigmatism, and the preoperative spherical equivalent (SEQ) ranged from -0.
View Article and Find Full Text PDFBackground: Single-step transepithelial photorefractive keratectomy (TPRK) is a modern refractive surgery technique that offers a no-touch approach for correcting myopia and astigmatism. This study aims to evaluate the short-term visual and refractive outcomes of TPRK in patients with myopia and astigmatism over a 6-month follow-up period.
Methods: This retrospective cohort study included patients who underwent single-step TPRK using the Amaris 750S laser platform with SmartSurf and SmartPulse technologies, targeting a plano refraction.
Clin Ophthalmol
October 2024
Anterior Segment Department, Miranza Begitek, Donostia-San Sebastián, Spain.
Purpose: To compare corneal aberrometry, densitometry, and refractive outcomes of single-step Transepithelial Photorefractive Keratectomy (Trans-PRK) with and without epithelial thickness customization.
Patients And Methods: This was a prospective, interventional, randomized controlled study. Patients undergoing Trans-PRK using the WaveLight EX500 laser with StreamLight software (Alcon Laboratories, Forth Worth, TX, USA) were randomly assigned to control (55 µm standard epithelial thickness) or customized (thinnest point of epithelial thickness for each patient) groups.
Int J Pharm
October 2024
Department of Pharmaceutical Technology, School of Pharmacy, Aristotle University of Thessaloniki, GR-54124 Thessaloniki, Greece; Center for Interdisciplinary Research and Innovation (CIRI-AUTH), Thessaloniki, Greece. Electronic address:
3D-printed dosage forms comprised of Carbopol and Eudragit were fabricated through semi-solid extrusion, combining Enoxaparin (Enox) and the permeation enhancer SNAC in a single-step process without subsequent post-processing. Inks were characterized using rheology and Fourier-transform infrared (FTIR) spectroscopy. The stability of Enox in the fabricated dosage forms was assessed by means of Nuclear Magnetic Resonance (NMR) and Circular Dichroism (CD) analysis.
View Article and Find Full Text PDFEur J Ophthalmol
August 2024
Miranza Begitek, Donostia-San Sebastián, Spain.
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