Demineralization of dental hard tissues is a well-known health issue and the primary mechanism responsible for caries and dentinal hypersensitivity. Remineralizing toothpastes are nowadays available to improve conventional oral care formulations regarding the prevention and repair of demineralization. In this paper, we analyzed the chemical-physical features of a commercial toothpaste (Biosmalto Caries Abrasion and Erosion, Curasept S.p.A., Saronno, Italy), with particular attention paid to the water-insoluble fraction which contains the remineralizing bioactive ingredients. Moreover, the efficacy of the toothpaste to induce enamel remineralization and to occlude dentinal tubules has been qualitatively and semiquantitatively tested in vitro on human dental tissues using scanning electron microscopy and X-ray microanalysis. Our results demonstrated that the water-insoluble fraction contained silica as well as chitosan and poorly crystalline biomimetic hydroxyapatite doped with carbonate, magnesium, strontium, and fluoride ions. The formulation showed excellent ability to restore demineralized enamel into its native structure by epitaxial deposition of a new crystalline phase in continuity with the native one. It was also able to occlude the dentinal tubules exposed completely by acid-etching. Overall, this study demonstrated that the tested toothpaste contained a biomimetic ionic-substituted hydroxyapatite-based active principle and that, within the in vitro conditions analyzed in this study, it was effective in dental hard tissue remineralization.
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http://dx.doi.org/10.3390/ma13132928 | DOI Listing |
Cureus
November 2024
Conservative Dentistry and Endodontics, Narayana Dental College and Hospital, Nelllore, IND.
Background: Dentin hypersensitivity (DH) is a common condition caused by exposed dentinal tubules, often requiring treatment with desensitizing agents. This in vitro study conducted at Narayana Dental College and Hospital (Nellore, AP, IND) between January 2022 and March 2022, aimed to evaluate the effectiveness of two desensitizing agents, SDI Riva Star (SDI Ltd., Bayswater, VIC, AUS) and Gluma Desensitizer (Kulzer, Hanau, DEU) in occluding dentinal tubules and their long-term durability following simulated brushing.
View Article and Find Full Text PDFCompend Contin Educ Dent
November 2024
Director Clinical Research, Colgate-Palmolive Co., Piscataway, New Jersey.
Background: Dentin hypersensitivity is a global oral health concern. This in vitro study and clinical evaluation tested the efficacy of 0.454% stannous fluoride toothpaste stabilized with nitrate and phosphates (SNaP) to occlude dentin and reduce dentin hypersensitivity.
View Article and Find Full Text PDFInt J Dent Hyg
October 2024
The University of Western Australia, Nedlands, Western Australia, Australia.
Aim: This in vitro study compared the effect of two commercially available silver diamine fluoride (SDF) products on dentinal tubule (DT) occlusion and dentin permeability.
Methods: Sixty-six dentin discs (1.0 mm thick) were divided equally into six groups: acid-etched with no treatment (negative control-NC), etched and sealed with nail varnish (positive control-PC), non-etched and treated with Advantage Arrest (AA), non-etched and treated with Topamine (TP), etched and treated with AA, and etched and treated with TP.
J Lasers Med Sci
September 2024
Department of Prosthodontics, Faculty of Dentistry, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.
Int Dent J
October 2024
Clinic of Operative Dentistry, Periodontology and Preventive Dentistry, Saarland University, Homburg/Saar, Germany.
Introduction And Aims: With the increasing prevalence of dentin hypersensitivity, more and more desensitizing agents with tubule-occluding properties are advocated in the market. The aim of the present study was to investigate the deposition of these agents on the dentin surface under in-situ conditions.
Methods: Bovine dentin specimens were pretreated with phosphoric acid and fixed to individual upper splints that were carried by up to 2 subjects for 3 min to allow pellicle formation.
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