In computed tomography, the mediastinum is split into ventral prevascular, middle visceral and dorsal paravertebral compartments. Each compartment contains specific tumours which will be presented and discussed briefly. The focus is on image-based analysis of morphological signs to differentiate between entities using X-rays, ultrasound, CT and MRI. It is however difficult to differentiate between various types of lesions based on morphology and to estimate the grade of malignancy. For this reason, functional imaging techniques like PET and MRI are essential tools for detailed and non-invasive work-up. If a histological tissue examination is required, these tissue samples can be acquired using CT guided biopsies with high diagnostic yield and low complication rates.
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http://dx.doi.org/10.1055/a-1171-2766 | DOI Listing |
J Clin Med
January 2025
Academic General Surgery Unit "V. Bonomo", Department of Precision and Regenerative Medicine and Jonian Area (DiMePRe-J), University of Bari "Aldo Moro" Medical School, 70124 Bari, Italy.
Surgical intervention in asymptomatic retrosternal goiter (RSG) is debated in the absence of suspicious cytology, while performing fine-needle aspiration (FNA) is challenging in thyroids with mediastinal extension. The rate of unexpected thyroid cancers found at the time of thyroidectomy varies widely, while the notion of increased cancer incidence in RSG with respect to cervical goiters is still controversial. We retrospectively reviewed 411 patients with a preoperative diagnosis of multinodular goiter (MNG) (114 retrosternal, 297 cervical) who underwent thyroidectomy at an academic endocrine surgery referral center between January 2019 and October 2022.
View Article and Find Full Text PDF: EnBloc resections of bone tumors of the spine are very demanding as the target to achieve a tumor-free margin specimen (sometimes impossible due to the extracompartimental tumor extension) is sometimes conflicting with the integrity of neurological functions and spine stability. : The surgical treatment of a huge multi-level chordoma of the thoracic spine with unusual extension is reported. Anteriorly, the tumor widely invaded the mediastinum and displaced the aorta; on the left side, it expanded in the subpleuric region; posteriorly, it was uncommonly distant 13 mm from the posterior wall.
View Article and Find Full Text PDFMedicina (Kaunas)
December 2024
Department of Respiratory Disease, Cukurova University Faculty of Medicine, Yüreğir, Adana 01250, Turkey.
: This study investigates the prevalence of calcification in mediastinal lymph nodes among sarcoidosis patients and the influencing factors. Sarcoidosis is a multisystemic inflammatory disease characterized by non-caseating epithelioid granulomas. Bilateral hilar lymphadenopathy (LAP) is the most common radiographic finding, with studies showing a correlation between the frequency of lymph node calcification and disease duration, with a frequency of 3% relating to a duration of 5 years and a frequency of 20% relating to one of 10 years.
View Article and Find Full Text PDFDiagnostics (Basel)
January 2025
Niculae Stancioiu Heart Institute, Calea Motilor 19-21, 400001 Cluj-Napoca, Romania.
Mediastinal tumors, regardless of their location, can grow to significant sizes, causing compression-related symptoms. The term "giant" mediastinal tumor is inconsistently defined in the literature. This study presents a new clinical-radiological classification (CRC) for mediastinal tumors and evaluates its applicability through a systematic review and a detailed case analysis of a giant thymolipoma.
View Article and Find Full Text PDFAnn Vasc Surg
January 2025
Department of Vascular Surgery, University Medical Center Utrecht, Utrecht, The Netherlands. Electronic address:
Introduction: Aorto-bronchial or aorto-pulmonary fistulas (ABPF) are a rare but life-threatening complication following thoracic endovascular aortic repair (TEVAR). This narrative review aims to provide an overview of the current trends and available evidence on ABPF following TEVAR, evaluating risk factors, diagnostic approaches, and possible preventive and therapeutic strategies.
Methods: Relevant publications on post-TEVAR ABPF were selected through a literature search on PubMed.
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