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Dissecting cellulitis mimicking kerion in a 9-year-old boy.
JAAD Case Rep
December 2024
Department of Dermatology, University of Connecticut School of Medicine, Farmington, Connecticut.
Differential diagnosis of posterior scalp hair loss.
Arch Dermatol Res
November 2024
Department of Dermatology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Compound Follicles in Folliculitis Decalvans Do Not Contain Vellus and Retained Telogen Follicles-A Pilot Histopathologic Series on Polytrichia.
J Cutan Pathol
January 2025
Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida, USA.
Article Synopsis
- - Polytrichia is a common observation in folliculitis decalvans (FD), linked to compound follicular structures (CFS) that involve multiple hair follicles sharing a single opening and surrounded by fibrous tissue.
- - A study analyzed 10 scalp biopsy samples from patients with early-stage FD, focusing on the types and quantities of follicles within these CFS.
- - The findings revealed that of 205 follicles examined, 156 were terminal follicles, primarily in the anagen phase, providing insights into the pathology of FD.
Evidence of IL-17-secreting mast cells in scalp lesions of folliculitis decalvans points to new therapeutic targets in recalcitrant lesions.
Clin Exp Dermatol
October 2024
Department of Dermatology, Hospital das Clínicas, University of São Paulo Medical School, São Paulo, Brazil.
Article Synopsis
- Folliculitis decalvans (FD) is a chronic hair loss condition with an unclear cause, but recent research indicates a link to IL-17 secretion by mast cells.
- A study found higher levels of IL-17 and mast cells in affected areas of the scalp compared to unaffected areas, suggesting an inflammatory response.
- The results indicate that targeting IL-17 and mast cells may help manage the chronic inflammation associated with severe cases of FD.
Dermoscopic Features of Dermatitis Cruris Pustulosa et Atrophicans: A Retrospective Study from a Tertiary Care Center in South India.
Indian Dermatol Online J
August 2024
Department of Dermatology and STD, National Institute of Medical Sciences and Research, Jaipur, Rajasthan, India.
Article Synopsis
- Dermatitis cruris pustulosa et atrophicans (DCPA) is a chronic skin condition that can lead to hair loss if not treated and is characterized by certain dermoscopic features that distinguish it from similar conditions.
- A study conducted on 30 patients in South India identified key dermoscopic findings such as follicular pustules, white structureless areas around follicles, and various vascular patterns, confirming the prevalence of DCPA in males and primarily affecting the lower limbs.
- Limitations of the study included its retrospective nature, small sample size, and absence of a comparison group, highlighting the need for further research to better understand DCPA and its features.
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