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Connections Across Open Water: A Bi-Organelle, Genomics-Scale Assessment of Atlantic-Wide Population Dynamics in a Pelagic, Endangered Apex Predator Shark ().
Evol Appl
January 2025
Save Our Seas Foundation Shark Research Center, Halmos College of Arts & Sciences Nova Southeastern University Dania Florida USA.
Large-bodied pelagic sharks are key regulators of oceanic ecosystem stability, but highly impacted by severe overfishing. One such species, the shortfin mako shark (), a globally widespread, highly migratory predator, has undergone dramatic population reductions and is now Endangered (IUCN Red List), with Atlantic Ocean mako sharks in particular assessed by fishery managers as overfished and in need of urgent, improved management attention. Genomic-scale population assessments for this apex predator species have not been previously available to inform management planning; thus, we investigated the population genetics of mako sharks across the Atlantic using a bi-organelle genomics approach.
View Article and Find Full Text PDFDual Blood Purification with CytoSorb and oXiris in Managing Recurrent Septic Shock: A Case Report.
Am J Case Rep
January 2025
Department of Anesthesiology and Intensive Care, Legionowo Hospital, Military Institute of Medicine - National Research Institute, Warsaw, Poland.
BACKGROUND Extracorporeal blood purification strategies were recently developed as adjunctive treatments for sepsis. CytoSorb® is an approved medical device designed to reduce blood levels of inflammatory cytokines. The oXiris high-adsorption membrane filter is used in continuous hemofiltration adsorption.
View Article and Find Full Text PDFPhenylboronic Acid-Modified Carbon Dot-Proteinase K Nanohybrids for Enhanced Photodynamic Therapy Against Bacterial Biofilm Infections.
Acta Biomater
January 2025
Department of radiology, Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu, 214122, China. Electronic address:
Nanohybrids combining phenylboronic acid-modified carbon dots (PCDs) and proteinase K have been engineered for addressing the formidable challenges of antimicrobial photodynamic therapy (aPDT) against bacterial biofilm infections, overcoming biofilm barrier obstruction, the limited diffusion of reactive oxygen species (ROS), and the inadequate ROS generation of traditional photosensitizers. PCDs are formulated for superior water solubility and robust singlet oxygen (O) production, mitigating issues related to dispersion and aggregation-induced quenching typical of conventional photosensitizers. The conjugation of phenylboronic acid to CDs not only enhanced O generation through increased electron-hole separation but also imparted strong bacterial binding capabilities to the PCDs, enabling broad-spectrum sterilization by maximizing the ROS-mediated bacterial destruction.
View Article and Find Full Text PDFSpatiotemporal estimates of anthropogenic NO emissions across China during 2015-2022 using a deep learning model.
J Hazard Mater
January 2025
Key Laboratory of Geographic Information Science of the Ministry of Education, School of Geographic Sciences, East China Normal University, Shanghai 200241, PR China; Institute of Eco-Chongming (IEC), 20 Cuiniao Road, Chenjia Town, Chongming District, Shanghai 202162, PR China. Electronic address:
As one of the significant air pollutants, nitrogen oxides (NO = NO + NO) not only pose a great threat to human health, but also contribute to the formation of secondary pollutants such as ozone and nitrate particles. Due to substantial uncertainties in bottom-up emission inventories, simulated concentrations of air pollutants using GEOS-Chem model often largely biased from those of ground-level observations. To address this issue, we developed a new deep learning model to simulate the inverse process of the GEOS-Chem model.
View Article and Find Full Text PDFGreen hydrogen is key to decarbonizing the world. But the costly, finicky devices that make it need dramatic improvement.
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