Cleft lip and/or palate patients (CLP) undergo corrective surgery that can affect facial growth. The aim of this study was to analyze facial growth and maxillary development of CLP subjects after surgery according to P.I.S.A. technique (Peri osteoplasty Improves Symmetry and Aesthetic). Cephalometric tracings of 55 patients were performed, thirty-three of which belonged to the test group, while the lasting twenty subjects were part of the control group. The test group was formed by cleft lip and/or palate patients after surgical repair according to P.I.S.A. technique. The control group included patients unaffected by this malformation, with an Angle's first class, selected from the Michigan Growth Study sample. Facial growth and upper maxilla development analysis was carried out by comparing the data obtained from the cephalometric traces of cleft patients who performed an early surgery, with the values of the same parameters measured in non-cleft subjects, providing the normal values. The results of this study showed, in the test group, a maxillary and mandibular bi-retrusion, a more negative facial convexity, the absence of a marked discrepancy in the skeletal relationships, a slight tendency towards hyper-divergence. .
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Food Res Int
February 2025
Department of Molecular Biology and Genetics, Aarhus University, 8000 Aarhus, Denmark. Electronic address:
Xanthine oxidase (XO) and lactoperoxidase (LPO) are highly abundant enzymes in milk. Their substrates, xanthine and thiocyanate, are found in elevated amounts in infant saliva, leading to a proposed interaction between milk and saliva referred to as the XO-LPO system. This system is suggested to generate reactive oxygen and nitrogen species with potential antibacterial effects.
View Article and Find Full Text PDFInt Arch Occup Environ Health
January 2025
Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Madrid, Spain.
Purpose: Mental health is a global public health challenge, with mental disorders being a major cause of morbidity. Particularly, taxi drivers face unique challenges related to long working hours, economic instability, and hazardous working conditions. To summarise the existing scientific literature on mental disorders in taxi drivers and identify associated variables.
View Article and Find Full Text PDFInj Prev
January 2025
Injury Prevention Research Center, School of Public Health, Shantou University, Shantou, Guangdong, China
Our manuscript reviewed the enormous number of deaths caused by different types of injuries in China and around the world and proposed a new motivation for injury prevention to address sharp demographic changes and promote constant economic growth when China faces ageing, fewer children and industrial upgrading.
View Article and Find Full Text PDFJ Pediatr Endocrinol Metab
January 2025
Pediatrics, Fondazione IRCCS San Gerardo Dei Tintori, Monza, Italy.
Objectives: Moebius syndrome (MS) is a rare congenital non-progressive rhombencephalic disorder mostly characterised by abducens and facial nerve palsy, but with a multifaceted clinical presentation. Isolated or multiple pituitary hormone deficiencies in the setting of MS have been occasionally reported, but the simultaneous involvement of three or more hypothalamic-pituitary axes has never been described. We hereby report the case of a girl with MS that showed a co-occurrence of GH-, TSH- and ACTH-deficiency.
View Article and Find Full Text PDFMethodsX
June 2025
School of Social Sciences, University of Tasmania, Tasmania 7005, Australia.
Researchers today face significant challenges reshaping the landscape of academic, government, and industry research due to the exponential growth of global research outputs and the advent of Generative Artificial Intelligence (GenAI). The annual increase in published works has made it difficult for traditional literature review and data analysis methods to keep pace, often rendering reviews outdated by the time of publication. In response, this methods article introduces a suite of new tools designed to automate a number of stages for systematic literature reviews.
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